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 External Resources

 nature.com/articles/ng.3765.pdfhttps://www.nature.com/articles/ng.3765.pdf  Article fulltext

 EGAS00001002193https://ega-archive.org/datasets/EGAS00001002193  EGA identifier (EGAS00001002193)

 gro-2/2874http://resolver.sub.uni-goettingen.de/purl?gro-2/2874  GRO.publications identifier

 0000-0002-9300-8399https://orcid.org/0000-0002-9300-8399  ORCID identifier (Christopher Gordon)

 0000-0003-2777-0198https://orcid.org/0000-0003-2777-0198  ORCID identifier (Gökhan Yigit)

 0000-0002-3381-7266https://orcid.org/0000-0002-3381-7266  ORCID identifier (Axel M. Hillmer)

 0000-0002-2984-1474https://orcid.org/0000-0002-2984-1474  ORCID identifier (Marnie E. Blewitt)

 0000-0003-2589-0364https://orcid.org/0000-0003-2589-0364  ORCID identifier (Bernd Wollnik)

 0000-0002-4070-7997https://orcid.org/0000-0002-4070-7997  ORCID identifier (Bruno Reversade)

 2CG9https://www.rcsb.org/structure/2CG9  RCSB PDB Identifier (2CG9)

 035xkbk20https://ror.org/035xkbk20  ROR identifier (035xkbk20, Aix-Marseille Université)

 05grdyy37https://ror.org/05grdyy37  ROR identifier (05grdyy37, Amsterdam University Medical Centers)

 02405mj67https://ror.org/02405mj67  ROR identifier (02405mj67, Belfast City Hospital)

 04c4bwh63https://ror.org/04c4bwh63  ROR identifier (04c4bwh63, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases)

 05k8wg936https://ror.org/05k8wg936  ROR identifier (05k8wg936, Genome Institute of Singapore)

 04kwvgz42https://ror.org/04kwvgz42  ROR identifier (04kwvgz42, Hacettepe University)

 03np4e098https://ror.org/03np4e098  ROR identifier (03np4e098, Haukeland University Hospital)

 05tr67282https://ror.org/05tr67282  ROR identifier (05tr67282, Hôpital Necker-Enfants Malades)

 05rq3rb55https://ror.org/05rq3rb55  ROR identifier (05rq3rb55, Institut des Maladies Génétiques Imagine)

 01ptsgx95https://ror.org/01ptsgx95  ROR identifier (01ptsgx95, Institut National d'Hygiène du Maroc)

 00jzwgz36https://ror.org/00jzwgz36  ROR identifier (00jzwgz36, Koç University)

 01znkr924https://ror.org/01znkr924  ROR identifier (01znkr924, Mahidol University)

 00r8w8f84https://ror.org/00r8w8f84  ROR identifier (00r8w8f84, Mohammed V University)

 058h74p94https://ror.org/058h74p94  ROR identifier (058h74p94, Nagasaki University)

 01tgyzw49https://ror.org/01tgyzw49  ROR identifier (01tgyzw49, National University of Singapore)

 04v2twj65https://ror.org/04v2twj65  ROR identifier (04v2twj65, Oxford Brookes University)

 04y0x0x35https://ror.org/04y0x0x35  ROR identifier (04y0x0x35, Queen Elizabeth University Hospital)

 01njes783https://ror.org/01njes783  ROR identifier (01njes783, Seattle Children's Hospital)

 02en5vm52https://ror.org/02en5vm52  ROR identifier (02en5vm52, Sorbonne Université)

 04fgpet95https://ror.org/04fgpet95  ROR identifier (04fgpet95, University Hospital of Wales)

 021ft0n22https://ror.org/021ft0n22  ROR identifier (021ft0n22, University Medical Center Göttingen)

 00rcxh774https://ror.org/00rcxh774  ROR identifier (00rcxh774, University of Cologne)

 00vtgdb53https://ror.org/00vtgdb53  ROR identifier (00vtgdb53, University of Glasgow)

 01ej9dk98https://ror.org/01ej9dk98  ROR identifier (01ej9dk98, University of Melbourne)

 00cvxb145https://ror.org/00cvxb145  ROR identifier (00cvxb145, University of Washington)

 01b6kha49https://ror.org/01b6kha49  ROR identifier (01b6kha49, Walter and Eliza Hall Institute of Medical Research)

 static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fng.3765/MediaObjects/41588_2017_BFng3765_MOESM283_ESM.pdf  Supplemental material

 vstatic-...M.xlsxvhttps://static-content.springer.com/esm/art%3A10.1038%2Fng.3765/MediaObjects/41588_2017_BFng3765_MOESM284_ESM.xlsx  Supplemental material (table)

 static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fng.3765/MediaObjects/41588_2017_BFng3765_MOESM285_ESM.xlsx  Supplemental material (table)

 Q29465788https://www.wikidata.org/wiki/Q29465788  Wikidata ID