Systematic and quantitative analysis of stop codon readthrough in Rett syndrome nonsense mutations |
| Lebeda D, Fierenz A, Werfel L, Rosin-Arbesfeld R, Hofhuis J, Thoms S | Journal of Molecular Medicine-JMM | 2024 | | |
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function |
| Gersch S, Lange T, (...), Toischer K | Clinical Research in Cardiology | 2024 | | |
3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes |
| Pochechueva TV, Schwenzer N, (...), Lehnart SE | International Journal of Molecular Sciences | 2024 | | |
Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions |
| Bloothooft M, Verbruggen B, Seibertz F, Heyden MAGvd, Voigt N, de Boer TP | Frontiers in Physiology | 2024 | | |
Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak |
| Dewenter M, Seitz T, (...), Neef S | ESC Heart Failure | 2024 | | |
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy | | Wali R, Xu H, (...), Ebert A | Biological Chemistry | 2024 | | |
Microtubules: highway to … arrhythmia? | | Liutkute A, Prosser BL, Voigt N | Cardiovasc Res | 2024 | | |
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts |
| Foo B, Amedei H, (...), Lehnart SE | bioRxiv | 2024 | | |
Through the Haze: Unveiling the Link Between Smoking and Atrial Fibrillation | | Mason FE, Voigt N | American Journal of Physiology-Heart and Circulatory Physiology | 2024 | | |
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling |
| Schoger E, Bleckwedel F, (...), Zelarayán LC | Communications Biology | 2024 | | |
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications | | Bode D, Pronto JRD, Schiattarella GG, Voigt N | Nature Reviews Cardiology | 2024 | | |
The importance of DNA sequence for nucleosome positioning in transcriptional regulation |
| Sahrhage M, Paul NB, Beißbarth T, Haubrock M | Life Science Alliance | 2024 | | |
Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresis | | Schröder S, Epple R, Fischer A, Schettler VJJ | Therapeutic Apheresis and Dialysis | 2024 | | |
Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function |
| Falcão‐Pires I, Ferreira AF, (...), Tocchetti CG | European Journal of Heart Failure | 2024 | | |
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation |
| Fakuade FE, Hubricht D, (...), Voigt N | Circulation | 2024 | | |
Patients with paradoxical low-flow, low-gradient aortic stenosis gain the least benefit from TAVI among all hemodynamic subtypes |
| Puls M, Beuthner BE, (...), Hasenfuß G | Clinical Research in Cardiology | 2024 | | |
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study |
| Talevi V, Melas K, (...), Breteler MM | Journal of Translational Medicine | 2024 | | |
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome |
| Busley AV, Gutiérrez-Gutiérrez O, (...), Cyganek L | Cell Reports | 2024 | | |
Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy | | Paulke NJ, Fleischhacker C, (...), Brandenburg S | Circulation Research | 2024 | | |
Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation |
| Kim R, Nagel SH, Liaw NY, Zimmermann W, Zelarayán LC, Schoger E | Stem Cell Research | 2024 | | |
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes |
| Amedei H, Paul NB, (...), Lenz C | Frontiers in Analytical Science | 2024 | | |
Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment | | Xu X, Tan X, (...), Hasenfuß G | Cardiovascular Research | 2024 | | |
Blood‐derived microRNAs are related to cognitive domains in the general population |
| Melas K, Talevi V, (...), Breteler MMB | Alzheimers & Dementia | 2024 | | |
Circulating microRNAs are related to cognitive domains in the general population |
| Melas K, Talevi V, (...), Breteler MM | medRxiv | 2024 | | |
Towards sustainable research data management of longitudinal, heterogeneous data from cardiac tissue engineering |
| Smolorz SA, Dittrich GM, (...), Kusch H | German Medical Science GMS Publishing House | 2024 | | |
Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness |
| Haertter D, Hauke L, Driehorst T, Nishi K, Zimmermann W, Schmidt CF | bioRxiv | 2024 | | |
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts |
| Ruiz-Orera J, Miller DC, (...), Hübner N | Nature Cardiovascular Research | 2024 | | |
Cardiac arrhythmias: the growing role of autoantibodies in diagnosis and treatment |
| Fakuade FE, Grune J, Voigt N | European Heart Journal | 2024 | | |
The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites |
| Zung N, Aravindan N, (...), Schuldiner M | bioRxiv | 2024 | | |
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes |
| Amedei H, Paul N, (...), Lenz C | bioRxiv | 2024 | | |
Addressing SARS-CoV-2 viroporins with antiarrhythmic drugs |
| Bloothooft M, Voigt N, de Boer TP | Europace | 2024 | | |
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts |
| Foo B, Amedei H, (...), Lehnart SE | PLoS One | 2024 | | |
Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes |
| Paasche A, Wiedmann F, (...), Schmidt C | Basic Research in Cardiology | 2024 | | |
Mapping Hierarchical File Structures to Semantic Data Models for Efficient Data Integration into Research Data Management Systems |
| tom Wörden H, Spreckelsen F, Luther S, Parlitz U, Schlemmer A | Data | 2024 | | |
High throughput methods for cardiac cellular electrophysiology studies: The road to personalized medicine | | Seibertz F, Voigt N | American Journal of Physiology-Heart and Circulatory Physiology | 2024 | | |
Epicardial adipose tissue as an independent predictor of long-term outcome in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement |
| Schulz A, Beuthner BE, (...), Schuster A | Clinical Research in Cardiology | 2024 | | |
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants |
| Knauer C, Haltern H, (...), Cyganek L | Molecular Therapy-Nucleic Acids | 2024 | | |
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction | | Gotthardt M, Lehnart SE | Cardiovascular Research | 2024 | | |
USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration |
| Prokakis E, Bamahmoud H, (...), Wegwitz F | Cell Communication and Signaling | 2024 | | |
Tissue-specific roles of peroxisomes revealed by expression meta-analysis |
| Plessner M, Thiele L, Hofhuis J, Thoms S | Biology Direct | 2024 | | |
Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement |
| Beuthner BE, Elkenani M, (...), Toischer K | ESC Heart Failure | 2024 | | |
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy |
| Schwenzer N, Tsukanov R, (...), Lehnart SE | bioRxiv | 2024 | | |
The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation |
| Pikunov AV, Syunyaev RA, (...), Efimov IR | bioRxiv | 2023 | | |
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes |
| Weber F, Klas S, (...), Cyganek L | Social Science Research Network | 2023 | | |
Approaching automation of multiple instance orchestration of the menoci web portal |
| Freckmann L, Henke C, (...), Kusch H | German Medical Science GMS Publishing House | 2023 | | |
Author Correction: Selective optogenetic control of Gq signaling using human Neuropsin | | Wagdi A, Malan D, (...), Bruegmann T | Nature Communications | 2023 | | |
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling |
| Schoger E, Bleckwedel F, (...), Zelarayán LC | Communications Biology | 2023 | | |
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome |
| Busley AV, Gutiérrez-Gutiérrez Ó, (...), Cyganek L | bioRxiv | 2023 | | |
GBA/GBN-position on the feedback of incidental findings in biobank-based research: consensus-based workflow for hospital-based biobanks |
| Geiger J, Fuchs J, (...), Jahns R | European Journal of Human Genetics | 2023 | | |
Defective COX1 expression in aging mice liver |
| Witte S, Boshnakovska A, Özdemir M, Chowdhury A, Rehling P, Aich A | Biology Open | 2023 | | |
Optical mapping of contracting hearts |
| Kappadan V, Sohi A, (...), Ng FS | The Journal of Physiology | 2023 | | |
DNA Methylation Analysis Identifies Novel Epigenetic Loci in Dilated Murine Heart upon Exposure to Volume Overload |
| Xu X, Elkenani M, (...), Mohamed BA | International Journal of Molecular Sciences | 2023 | | |
The history-dependent features of muscle force production: A challenge to the cross-bridge theory and their functional implications | | Hahn D, Han S, Joumaa V | Journal of Biomechanics | 2023 | | |
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart |
| Nanadikar MS, Vergel Leon AM, (...), Katschinski DM | Nature Communications | 2023 | | |
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V |
| Viktoria Busley A, Kleinsorge M, Cyganek L | Stem Cell Research | 2023 | | |
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V |
| Busley AV, Cyganek L | Stem Cell Research | 2023 | | |
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes | | Dai Y, Ignatyeva N, (...), Ebert A | Circulation Research | 2023 | | |
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues |
| Nakhaei-Rad S, Haghighi F, (...), Ahmadian MR | Communications Biology | 2023 | | |
Molecular and Functional Relevance of NaV1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model |
| Hartmann N, Knierim M, (...), Streckfuss-Bömeke K | International Journal of Molecular Sciences | 2023 | | |
Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC) |
| Priesmeier L, Schoger E, Cyganek L, Cecilia Zelarayán L | Stem Cell Research | 2023 | | |
Vicious Twins: RyR2 Dysfunction and Structural Remodeling | | Voigt N, Seibertz F, Fakuade FE | Circulation Research | 2023 | | |
Live-Cell Imaging of Peroxisomal Calcium Levels and Dynamics | | Sargsyan Y, Thoms S | Methods Mol Biol | 2023 | | |
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome |
| Chowdhury A, Boshnakovska A, (...), Rehling P | EMBO Molecular Medicine | 2023 | | |
Mapping hierarchical file structures to semantic data models for efficient data integration into research data management systems |
| Tom Wörden H, Spreckelsen F, Luther S, Parlitz U, Schlemmer A | Preprints | 2023 | | |
Bioengineering of a human innervated cardiac muscle model |
| Schneider LV, Bao G, (...), Zafeiriou M | bioRxiv | 2023 | | |
Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine |
| Mustroph J, Baier MJ, (...), Neef S | Circulation | 2023 | | |
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development |
| Seibertz F, Rubio T, (...), Voigt N | Cardiovascular Research | 2023 | | |
RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer |
| Prokakis E, Jansari S, (...), Wegwitz F | Cell Death & Disease | 2023 | | |
4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applications |
| Goodarzi Hosseinabadi H, Biswas A, (...), Ionov L | Small | 2023 | | |
Metabolomic Profiling in Patients with Different Hemodynamic Subtypes of Severe Aortic Valve Stenosis |
| Bengel P, Elkenani M, (...), Schnelle M | Biomolecules | 2023 | | |
Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement |
| Evertz R, Hub S, (...), Schuster A | ESC Heart Failure | 2023 | | |
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs |
| Shi R, Reichardt M, (...), Brügmann T | Cardiovascular Research | 2023 | | |
Titin governs myocardial passive stiffness with major support from microtubules and actin and the extracellular matrix |
| Loescher CM, Freundt JK, (...), Linke WA | Nature Cardiovascular Research | 2023 | | |
Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome |
| Kutschka I, Bertero E, (...), Dudek J | Basic Research in Cardiology | 2023 | | |
Regulatory roles of the N6-methyladenosine demethylase FTO in cardiac remodeling |
| Annamalai K, Buchholz E, Castro R, Panyam N, Fischer A, Toischer K | European Heart Journal | 2023 | | |
Approaching automation of multiple instance orchestration of the menoci web portal |
| Freckmann L, Henke C, (...), Kusch H | Bausteine Forschungsdatenmanagement | 2023 | | |
A dual-targeted drug inhibits cardiac ryanodine receptor Ca<sup>2+</sup>leak but activates SERCA2a Ca<sup>2+</sup>uptake |
| Wegener JW, Mitronova GY, (...), Lehnart SE | Life Science Alliance | 2023 | | |
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy |
| Kyriakopoulou E, Versteeg D, (...), van Rooij E | Nature Cardiovascular Research | 2023 | | |
Dissolution of spiral wave’s core using cardiac optogenetics |
| Hussaini S, Lädke SL, (...), Luther S | PLOS Computational Biology | 2023 | | |
Enlightening Cardiac Arrhythmia with Optogenetics | | Bruegmann T, Boyle PM, Schneider-Warme F | Heart Rate and Rhythm | 2023 | | |
Titin takes centerstage among cytoskeletal contributions to myocardial passive stiffness |
| Loescher CM, Linke WA | Cytoskeleton | 2023 | | |
Protocol to develop force-generating human skeletal muscle organoids |
| Shahriyari M, Rinn M, Hofemeier AD, Babych A, Zimmermann W, Tiburcy M | STAR Protocols | 2023 | | |
Implications for neutrophils in cardiac arrhythmias | | Hegemann N, Barth L, Doering Y, Voigt N, Grune J | American Journal of Physiology-Heart and Circulatory Physiology | 2023 | | |
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine |
| Schoger E, Lelek S, Panáková D, Zelarayán LC | Frontiers in Cardiovascular Medicine | 2022 | | |
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells |
| Pavez-Giani MG, Cyganek L | Frontiers in Cell and Developmental Biology | 2022 | | |
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes |
| Brandenburg S, Pawlowitz J, (...), Lehnart SE | Journal of Molecular and Cellular Cardiology | 2022 | | |
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells |
| Oleksiievets N, Sargsyan Y, (...), Tsukanov R | Communications Biology | 2022 | | |
Human–Device Interaction in the Life Science Laboratory | | Söldner R, Rheinländer S, Meyer T, Olszowy M, Austerjost J | Advances in Biochemical Engineering-Biotechnology | 2022 | | |
Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration |
| Li W, Luo X, (...), Schubert M | Pharmaceuticals | 2022 | | |
Modulatorische Einheiten bei Herzinsuffizienz |
| Hasenfuß G, Kaul A, Lehnart SE, Linke WA, Zelarayán LC, Zimmermann W | Der Kardiologe | 2022 | | |
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease |
| Shomroni O, Sitte M, (...), Salinas G | Scientific Reports | 2022 | | |
Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation |
| Hartmann N, Preuß L, (...), Toischer K | ESC Heart Failure | 2022 | | |
Selective optogenetic control of Gq signaling using human Neuropsin |
| Wagdi A, Malan D, (...), Bruegmann T | Nature Communications | 2022 | | |
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation – A proof-of-concept study | | Jebran A, Tiburcy M, (...), Zimmermann W | Journal of Molecular and Cellular Cardiology | 2022 | | |
The Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular Disease |
| Zschüntzsch J, Meyer S, (...), Tiburcy M | Cells | 2022 | | |
Herzinsuffizienz |
| Herting J, Fischer TH, Maack C | Nephrologe | 2022 | | |
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy | | Jung P, Seibertz F, (...), Voigt N | Basic Research in Cardiology | 2022 | | |
IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress |
| Nanadikar M, Leon AV, (...), Katschinski D | Researchsquare | 2022 | | |
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair | | Tiburcy M, Meyer T, Satin P, Zimmermann W | Methods in Molecular Biology | 2022 | | |
Background calcium influx in arrhythmia: lead actor or extra? |
| Fakuade FE, Fauconnier J, Voigt N | Journal of Physiology-London | 2022 | | |
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes |
| Weninger G, Pochechueva T, (...), Lehnart SE | Scientific Reports | 2022 | | |
Not the classical serendipity: does doxapram treat atrial fibrillation? | | Liutkute A, Brundel BJJM, Voigt N | Cardiovasc Res | 2022 | | |
Remote control of the heart and beyond | | Zimmermann W | Science | 2022 | | |
Effects of Atrial Fibrillation on the Human Ventricle |
| Pabel S, Knierim M, (...), Sossalla S | Circulation Research | 2022 | | |
A Mathematical Model for Electrical Activity in Pig Atrial Tissue |
| Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R | Frontiers in Physiology | 2022 | | |
RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes |
| Levay MK, Krobert KA, (...), Wieland T | Basic Research in Cardiology | 2022 | | |
Spatiotemporal Organization of Electromechanical Phase Singularities during High-Frequency Cardiac Arrhythmias |
| Molavi Tabrizi A, Mesgarnejad A, Bazzi M, Luther S, Christoph J, Karma A | Physical Review X | 2022 | | |
Hemodynamic stress‐induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein |
| Mohamed BA, Elkenani M, (...), Toischer K | Journal of Cellular and Molecular Medicine | 2022 | | |
A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming |
| Lyra-Leite DM, Gutiérrez-Gutiérrez O, Wang M, Zhou Y, Cyganek L, Burridge PW | STAR Protocols | 2022 | | |
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis |
| Brandenburg S, Otto L, (...), Lehnart SE | Journal of Molecular and Cellular Cardiology | 2022 | | |
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes |
| Seibertz F, Rapedius M, (...), Voigt N | Communications Biology | 2022 | | |
Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study |
| Lange T, Backhaus SJ, (...), Schuster A | Journal of Cardiovascular Magnetic Resonance | 2022 | | |
There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments |
| Rapedius M, Obergrussberger A, (...), Fertig N | Frontiers in Molecular Neuroscience | 2022 | | |
Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling |
| Paulke N, Amlaz S, (...), Brandenburg S | European Heart Journal | 2022 | | |
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy |
| Shahriyari M, Islam MR, (...), Tiburcy M | Journal of Cachexia Sarcopenia and Muscle | 2022 | | |
Titin force in muscle cells alters lattice order, thick and thin filament protein formation | | Hessel AL, Ma W, (...), Linke WA | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues | | Santos GL, DeGrave AN, (...), Lutz S | Biomaterials Advances | 2022 | | |
Calcium in peroxisomes: An essential messenger in an essential cell organelle |
| Sargsyan Y, Kalinowski J, Thoms S | Frontiers in Cell and Developmental Biology | 2022 | | |
Editorial: Cardiac optogenetics: Using light to observe and excite the heart |
| Bruegmann T, Smith GL, Lehnart SE | Frontiers in Physiology | 2022 | | |
Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation | | Voigt N, Maack C, Pronto JRD | Journal of the American College of Cardiology | 2022 | | |
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp |
| Rosholm KR, Badone B, (...), Bell DC | Frontiers in Molecular Neuroscience | 2022 | | |
An optimized protocol for the enrichment of small vesicles from murine and non-human primate heart tissue |
| Bleckwedel F, Germena G, Hinkel R, Zelarayán LC | Trillium extracellular vesicles | 2022 | | |
Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs |
| Nakhaei-Rad S, Bazgir F, (...), Ahmadian MR | bioRxiv | 2022 | | |
NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overload | | Schnelle M, Sawyer I, (...), Shah AM | Cardiovascular Research | 2021 | | |
Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast Interactions | | Zimmermann W | Circulation Research | 2021 | | |
5.3 Kollaboratives Arbeiten mit Daten |
| Engelhardt C, Kusch H | Praxishandbuch Forschungsdatenmanagement | 2021 | | |
Online Supplemental Files for "Caveolin3 Stabilizes McT1-mediated Lactate/Proton Transport in Cardiomyocytes" |
| Lehnart SE | Göttingen Research Online (Data.GRO) | 2021 | | |
Epigenetic gene expression links heart failure to memory impairment |
| Islam MR, Lbik D, (...), Fischer A | EMBO Molecular Medicine | 2021 | | |
Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes |
| Peper J, Kownatzki-Danger D, (...), Lehnart SE | Circulation Research | 2021 | | |
Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition |
| Hakroush S, Kopp SB, (...), Tampe B | Frontiers in Immunology | 2021 | | |
Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes |
| Kittana N, Assali M, (...), Lutz S | International Journal of Nanomedicine | 2021 | | |
Monitoring mitochondrial translation in living cells |
| Yousefi R, Fornasiero EF, (...), Pacheu‐Grau D | EMBO reports | 2021 | | |
Sustainable Deployment of Research Infrastructure Components |
| Bender T, Parciak M, Suhr M, Sax U, Bauer CR | German Medical Science GMS Publishing House | 2021 | | |
Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control | | Hoffmann S, Schmitteckert S, (...), Rappold G | Biochimica et Biophysica Acta-Gene Regulatory Mechanisms | 2021 | | |
RhoGEF17 - An Essential Regulator of Endothelial Cell Death and Growth |
| Weber P, Baltus D, (...), Lutz S | Cells | 2021 | | |
Predicting the duration of chaotic transients in excitable media |
| Aron M, Lilienkamp T, Luther S, Parlitz U | Journal of Physics-Complexity | 2021 | | |
cAMP Imaging at Ryanodine Receptors Reveals β2-Adrenoceptor Driven Arrhythmias |
| Berisha F, Götz K, (...), Nikolaev VO | Circulation Research | 2021 | | |
Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7 ‐related osteopetrosis |
| Rössler U, Hennig AF, (...), Kornak U | Journal of Bone and Mineral Research | 2021 | | |
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci |
| Kyryachenko S, Georges A, (...), Bouatia-Naji N | Circulation Research | 2021 | | |
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state |
| Yigit G, Sheffer R, (...), Brockmann K | Journal of Medical Genetics | 2021 | | |
Unraveling the mysteries of the titin–N2A signalosome |
| Hessel AL, Linke WA | Journal of General Physiology | 2021 | | |
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation |
| Sadredini M, Haugsten Hansen M, (...), Stokke MK | American Journal of Physiology-Heart and Circulatory Physiology | 2021 | | |
TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes |
| Sattler K, El-Battrawy I, (...), Akin I | Scientific Reports | 2021 | | |
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression |
| Schoger E, Zimmermann W, Cyganek L, Zelarayán LC | Stem Cell Research | 2021 | | |
Organs-on-chip models for cardiovascular drug development |
| Zimmermann W | Cardiovascular Research | 2021 | | |
Fibroblast Derived Human Engineered Connective Tissue for Screening Applications | | Santos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz S | Journal of Visualized Experiments | 2021 | | |
Management of Metadata Types in Basic Cardiological Research |
| Kusch H, Kossen R, (...), Nussbeck SY | Studies in Health Technology and Informatics | 2021 | | |
Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice |
| Chen Y, Lüttmann FF, (...), Braun T | Science | 2021 | | |
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1. |
| Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MK | Physiological Reports | 2021 | | |
Biallelic variants in YRDC cause a developmental disorder with progeroid features |
| Schmidt J, Goergens J, (...), Wollnik B | Human Genetics | 2021 | | |
GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072 |
| Kusch H, Bauer CR, (...), Sax U | Göttingen Research Online (Data.GRO) | 2021 | | |
Pulsed low-energy stimulation initiates electric turbulence in cardiac tissue |
| Majumder R, Hussaini S, Zykov VS, Luther S, Bodenschatz E | PLOS Computational Biology | 2021 | | |
A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease |
| Shomroni O, Sitte M, (...), Salinas G | Researchsquare | 2021 | | |
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy |
| Bertero E, Nickel A, (...), Maack C | Circulation | 2021 | | |
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations | | Fomin A, Gärtner A, (...), Linke WA | Science Translational Medicine | 2021 | | |
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure |
| Bengel P, Dybkova N, (...), Sossalla S | Nature Communications | 2021 | | |
Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: From molecular mechanisms to therapeutic targets |
| Boer RA, Heymans S, (...), Thum T | European Journal of Heart Failure | 2021 | | |
Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity |
| Shahriyari M, Islam MR, (...), Tiburcy M | bioRxiv | 2021 | | |
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation |
| Schoger E, Zimmermann W, Cyganek L, Zelarayán LC | Stem Cell Research | 2021 | | |
The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool |
| Wegener JW, Wagdi A, (...), Lehnart SE | Frontiers in Physiology | 2021 | | |
Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
| Zheng X, Zhang L, (...), Doeppner TR | Translational Stroke Research | 2021 | | |
Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy |
| Yigit G, Wollnik B | Medizinische Genetik | 2021 | | |
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells |
| Sargsyan Y, Bickmeyer U, Gibhardt CS, Streckfuss-Bömeke K, Bogeski I, Thoms S | Life Science Alliance | 2021 | | |
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy |
| Xu H, Wali R, (...), Ebert A | FEBS Letters | 2021 | | |
Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation |
| Fakuade FE, Steckmeister V, (...), Voigt N | Cardiovascular Research | 2020 | | |
Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients |
| Dai Y, Amenov A, (...), Ebert A | Scientific Reports | 2020 | | |
Epigenetic gene-expression links heart failure to memory impairment |
| Islam R, Lbik D, (...), Fischer A | bioRxiv | 2020 | | |
COA6 facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria |
| Pacheu-Grau D, Wasilewski M, (...), Rehling R | Journal of Molecular Biology | 2020 | | |
Interdisciplinary Research on Aortic Valve Stenosis: a Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement |
| Beuthner BEC, Topci R, (...), Nussbeck SY | Open Journal of Bioresources | 2020 | | |
Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis |
| Puls M, Beuthner BE, (...), Hasenfuß G | European Heart Journal | 2020 | | |
menoci: Lightweight Extensible Web Portal enabling FAIR Data Management for Biomedical Research Projects |
| Suhr M, Lehmann C, (...), Nußbeck SY | arXiv | 2020 | | |
Tissue Engineered Heart Repair from Preclinical Models to First-in-Patient Studies | | Zimmermann W | Current Opinion in Physiology | 2020 | | |
Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon |
| Zambusi A, Burhan ÖP, Di Giaimo R, Schmid B, Ninkovic J | Cells | 2020 | | |
Functions of Vertebrate Ferlins | | Bulankina AV, Thoms S | Cells | 2020 | | |
Inhibition of NaV1.8 Prevents Atrial Arrhythmogenesis in Human and Mice |
| Pabel S, Ahmad S, (...), Sossalla S | Basic Research in Cardiology | 2020 | | |
CRISPLD1: a novel conserved target in the transition to human heart failure |
| Khadjeh S, Hindmarsh V, (...), Hasenfuss G | Basic Research in Cardiology | 2020 | | |
Excitable Dynamics in Neural and Cardiac Systems | | Barrio R, Coombes S, Desroches M, Fenton F, Luther S, Pueyo E | Communications in Nonlinear Science and Numerical Simulation | 2020 | | |
Guidelines for a Standardized File Structure for Scientific Data |
| Spreckelsen F, Rüchardt B, Lebert J, Luther S, Parlitz U, Schlemmer A | Preprints | 2020 | | |
Guidelines for a Standardized Filesystem Layout for Scientific Data |
| Spreckelsen F, Rüchardt B, Lebert J, Luther S, Parlitz U, Schlemmer A | Data | 2020 | | |
Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
| Zheng X, Zhang L, (...), Doeppner TR | Translational Stroke Research | 2020 | | |
Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy |
| Zschüntzsch J, Jouvenal PV, (...), Schmidt J | Journal of Cachexia Sarcopenia and Muscle | 2020 | | |
Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes |
| Kleinsorge M, Cyganek L | STAR Protocols | 2020 | | |
Generation of Engineered Human Myocardium in a Multi-well Format |
| Tiburcy M, Meyer T, Liaw NY, Zimmermann W | STAR Protocols | 2020 | | |
Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice |
| Rudolph F, Fink C, (...), Gotthardt M | Nature Communications | 2020 | | |
Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis |
| Backhaus SJ, Lange T, (...), Schuster A | Journal of Cardiovascular Magnetic Resonance | 2020 | | |
Dysferlin links excitation–contraction coupling to structure and maintenance of the cardiac transverse–axial tubule system | | Hofhuis J, Bersch K, (...), Thoms S | Europace | 2020 | | |
Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated Cardiomyopathy | | Hanses U, Kleinsorge M, (...), Cyganek L | Circulation | 2020 | | |
Loss of SPEG Inhibitory Phosphorylation of RyR2 Promotes Atrial Fibrillation | | Campbell HM, Quick AP, (...), Wehrens XH | Circulation | 2020 | | |
Sacubitrilat reduces pro‐arrhythmogenic sarcoplasmic reticulum Ca2+ leak in human ventricular cardiomyocytes of patients with end‐stage heart failure |
| Eiringhaus J, Wünsche CM, (...), Fischer TH | ESC Heart Failure | 2020 | | |
Insights into latest cardiovascular research at scientific institutions in Göttingen and Heidelberg: a report by the ESC Scientists of Tomorrow |
| Schmidt C, Voigt N | Cardiovascular Research | 2020 | | |
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids |
| Zafeiriou M, Bao G, (...), Zimmermann W | Nature Communications | 2020 | | |
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation |
| Schoger E, Argyriou L, Cyganek L, Zelarayán LC | Stem Cell Research | 2020 | | |
IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency |
| Luo X, Li W, (...), Guan K | Frontiers in Cell and Developmental Biology | 2020 | | |
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban | | Menzel J, Kownatzki-Danger D, (...), Schwappach B | Science Signaling | 2020 | | |
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin |
| Swist S, Unger A, (...), Linke WA | Nature Communications | 2020 | | |
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide | | Montiel V, Bella R, (...), Balligand J | Science Translational Medicine | 2020 | | |
Inhibition of Prolyl-Hydroxylase Domain Enzymes Protects From Reoxygenation Injury in Engineered Human Myocardium | | Levent E, Noack C, Zelarayán LC, Katschinski DM, Zimmermann W, Tiburcy M | Circulation | 2020 | | |
Alexa, do science! Voice-activated assistants hit the lab bench |
| Perkel JM | Nature | 2020 | | |
Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine |
| Pan Z, Ebert A, Liang P | Pflugers Archiv-European Journal of Physiology | 2020 | | |
Menoci: lightweight extensible web portal enhancing data management for biomedical research projects |
| Suhr M, Lehmann C, (...), Nussbeck SY | BMC Bioinformatics | 2020 | | |
Cellular and mitochondrial mechanisms of atrial fibrillation |
| Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N | Basic Research in Cardiology | 2020 | | |
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control |
| Rathjens FS, Blenkle A, (...), Zafeiriou M | Cardiovascular Research | 2020 | | |
Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis |
| Ganapathi M, Argyriou L, (...), Wollnik B | Human Genetics | 2020 | | |
Local translation in synaptic mitochondria influences synaptic transmission |
| Yousefi R, Fornasiero EF, (...), Pacheu-Grau D | bioRxiv | 2020 | | |
Connexin hemichannels in atrial fibrillation: orphaned and irrelevant? |
| Fakuade FE, Tomsits P, Voigt N | Cardiovascular Research | 2020 | | |
Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium Current | | Tomsits P, Schüttler D, Kääb S, Clauss S, Voigt N | Journal of Visualized Experiments | 2020 | | |
CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect |
| Reil JC, Reil GH, (...), Hamdani N | Journal of Physiology-London | 2020 | | |
Integrated Ca2+ flux and AFM force analysis in human iPSC-derived cardiomyocytes | | Malkovskiy AV, Ignatyeva N, Dai Y, Hasenfuss G, Rajadas J, Ebert A | Biological Chemistry | 2020 | | |
Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling |
| Eiringhaus J, Herting J, (...), Fischer TH | Basic Research in Cardiology | 2019 | | |
ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure |
| Madonna R, Van Laake LW, (...), Sluijter JPG | Cardiovascular Research | 2019 | | |
O2 affects mitochondrial functionality ex vivo |
| Nanadikar MS, Vergel Leon AM, (...), Katschinski DM | Redox Biology | 2019 | | |
Cardiac macrotissues-on-a-plate models for phenotypic drug screens | | Meyer T, Tiburcy M, Zimmermann W | Advanced Drug Delivery Reviews | 2019 | | |
N-glycosylation-dependent regulation of hK2P17.1 currents |
| Wiedmann F, Schlund D, (...), Schmidt C | Molecular Biology of the Cell | 2019 | | |
Posttranslational modifications of titin from cardiac muscle: how, where and what for? |
| Koser F, Loescher C, Linke WA | FEBS Journal | 2019 | | |
Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium |
| Trautsch I, Heta E, (...), Zimmermann W | Frontiers in Physiology | 2019 | | |
Engineered Heart Tissue Models from hiPSC-Derived Cardiomyocytes and Cardiac ECM for Disease Modeling and Drug Testing Applications | | Goldfracht I, Efraim Y, (...), Gepstein L | Acta Biomaterialia | 2019 | | |
Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis |
| Brandenburg S, Pawlowitz J, (...), Lehnart SE | JCI Insight | 2019 | | |
Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes |
| Ebert A, Joshi AU, (...), Wu JC | Circulation Research | 2019 | | |
Drug Testing in Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1 | | Zhao Z, Li X, (...), Borggrefe M | Clinical Pharmacology and Therapeutics | 2019 | | |
The Translational Landscape of the Human Heart | | van Heesch S, Witte F, (...), Hubner N | Cell | 2019 | | |
The Ways of Tails: the GET Pathway and more | | Borgese N, Coy-Vergara J, Colombo SF, Schwappach B | Protein Journal | 2019 | | |
CaosDB—Research Data Management for Complex, Changing, and Automated Research Workflows |
| Fitschen T, Schlemmer A, Hornung D, tom Wörden H, Parlitz U, Luther S | Data | 2019 | | |
Simultaneous unpinning of multiple vortices in two-dimensional excitable media |
| tom Wörden H, Parlitz U, Luther S | Physical Review E | 2019 | | |
Workshop on data management costs and efforts, 28 May 2019 in Göttingen |
| Roertgen S, Kusch H, (...), Ebert B | Göttingen Research Online (Data.GRO) | 2019 | | |
Scientists on the Spot: Autophagy and heart disease |
| Voigt N, Sadoshima J | Cardiovascular Research | 2019 | | |
Genetic deletion of calcium/calmodulin-dependent protein kinase type II delta does not mitigate adverse myocardial remodeling in volume-overloaded hearts |
| Mohamed BA, Elkenani M, (...), Toischer K | Scientific Reports | 2019 | | |
Assessing the role of extracellular signal‐regulated kinases 1 and 2 in volume overload‐induced cardiac remodelling |
| Jochmann S, Elkenani M, (...), Schnelle M | ESC Heart Failure | 2019 | | |
KLF15-Wnt–Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart |
| Noack C, Iyer LM, (...), Zelarayán LC | Journal of the American College of Cardiology | 2019 | | |
Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function | | Zaunbrecher RJ, Abel AN, (...), Murry CE | Circulation | 2019 | | |
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation | | Alsina KM, Hulsurkar M, (...), Wehrens XH | Circulation | 2019 | | |
A trap mutant reveals the physiological client spectrum of TRC40 |
| Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B | Journal of Cell Science | 2019 | | |
Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues |
| Santos GL, Hartmann S, Zimmermann W, Ridley A, Lutz S | Journal of Molecular and Cellular Cardiology | 2019 | | |
Cardiac Tissue Engineering as Use Case to Connect Biomedical Research Laboratories to an Emerging Global Data Infrastructure |
| Suhr M, Umbach N, Meyer T, Zimmermann WH, Sax U | Studies in Health Technology and Informatics | 2019 | | |
Arzneimittelinteraktionen, die man kennen muss! |
| Voigt N, Ort K, Sossalla S | Fortschritte der Neurologie Psychiatrie | 2019 | | |
Blut und Urin Begleitschein |
| Nußbeck S | Göttingen Research Online (Data.GRO) | 2019 | | |
Protokoll Myokardbiopsien |
| Nußbeck S | Göttingen Research Online (Data.GRO) | 2019 | | |
Protokoll Blut- und Uringewinnung und -verarbeitung |
| Nußbeck S | Göttingen Research Online (Data.GRO) | 2019 | | |
Spiral wave unpinning facilitated by wave emitting sites in cardiac monolayers | | Punacha S, Berg S, Sebastian A, Krinski VI, Luther S, Shajahan TK | Proceedings of the Royal Society A-Mathematical Physical and Engineering Sciences | 2019 | | |
Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish |
| Burczyk MS, Burkhalter MD, (...), Philipp M | JCI Insight | 2019 | | |
P1235 Acetylcholine-activated inward-rectifier potassium currents in atrial cardiomyocytes derived from induced pluripotent stem cells and atrial engineered heart muscle preparations | | Springer R, Seibertz F, (...), Voigt N | European Heart Journal | 2019 | | |
P1621 m6A RNA-methylation in the progression of heart failure | | Buchholz E, Berulava T, (...), Toischer K | European Heart Journal | 2019 | | |
P5998 The Phosphodiesterase 4D interacting protein averts volume overload - but not pressure overload-induced pathological myocardial remodeling | | Mohamed BA, Elkenani M, Jakubiczka-Smorag J, Bader M, Hasenfuß G, Toischer K | European Heart Journal | 2019 | | |
P3829 Antiarrhythmic effects of Sacubitrilat (LBQ657) on Ca2+ homeostasis in ventricular cardiomyocytes | | Eiringhaus J, Wuensche C, Herting J, Hasenfuß G, Sossalla S, Fischer T | European Heart Journal | 2019 | | |
1180 Cardiomyocyte-specific deletion of Brd4 induces hypertrophic cardiomyopathy and suggests a novel function for the chromatin reader as co-repressor in the healthy heart | | Lbik D, Buchholz E, Mohamed B, Fischer A, Hasenfuß G, Toischer K | European Heart Journal | 2019 | | |
Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes |
| Sattler K, El-Battrawy I, (...), Akin I | Scientific Reports | 2019 | | |
A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes | | El-Battrawy I, Albers S, (...), Akin I | Europace | 2019 | | |
A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods |
| Hübscher D, Rebs S, (...), Streckfuß-Bömeke K | Stem Cells International | 2019 | | |
CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart |
| Schoger E, Carroll KJ, (...), Zelarayán LC | Circulation Research | 2019 | | |
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation |
| Berulava T, Buchholz E, (...), Toischer K | European Journal of Heart Failure | 2019 | | |
51Cr-release to monitor NK cell cytotoxicity | | Elsner L, Dressel R | Methods in Enzymology | 2019 | | |
Staying in Healthy Contact: How Peroxisomes Interact with Other Cell Organelles | | Sargsyan Y, Thoms S | Trends in Molecular Medicine | 2019 | | |
Leaving spreadsheets behind – FAIR documentation and representation of human stem cell lines in the Collaborative Research Centre 1002 |
| Lehmann C, Suhr M, (...), Kusch H | German Medical Science GMS Publishing House | 2019 | | |
Towards standardized documentation of mouse lines in biomedical basic research |
| Rheinländer S, Aschenbrandt G, Nussbeck SY, Suhr M, Kusch H | German Medical Science GMS Publishing House | 2019 | | |
Regeneration competent satellite cell niches in rat engineered skeletal muscle |
| Tiburcy M, Markov A, (...), Zimmermann W | FASEB BioAdvances | 2019 | | |
Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1 | | Antunes D, Chowdhury A, (...), Rapaport D | Journal of Molecular Medicine-JMM | 2019 | | |
Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling |
| Gogiraju R, Hubert A, (...), Schäfer K | Circulation-Heart Failure | 2019 | | |
Arzneimittelinteraktionen, die man kennen muss! | | Voigt N, Ort K, Sossalla S | Deutsche Medizinische Wochenschrift | 2019 | | |
Posters presented at "Workshop zu Forschungsdatenmanagement und -infrastruktur in DFG-Sonderforschungsbereichen", 26./27. November 2018 in Göttingen |
| Roertgen S, Kusch H, (...), Schwandt S | Göttingen Research Online (Data.GRO) | 2019 | | |
Presentations and material of "Workshop zu Forschungsdatenmanagement und -infrastruktur in DFG-Sonderforschungsbereichen", 26./27. November 2018 in Göttingen |
| Roertgen S, Kusch H, (...), Schwandt S | Göttingen Research Online (Data.GRO) | 2019 | | |
Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular Microdomains | | Bastug Z, Nikolaev VO | Cyclic Nucleotide Signaling | 2018 | | |
Modeling Short QT Syndrome Using Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes |
| El‐Battrawy I, Lan H, (...), Akin I | Journal of the American Heart Association | 2018 | | |
Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy | | El-Battrawy I, Zhao Z, (...), Akin I | Europace | 2018 | | |
P2835 Low-energy control of spatiotemporal cardiac dynamics using structured photo-stimulation |
| Quinonez Uribe RA, Luther S, Richter C | European Heart Journal | 2018 | | |
Axial Tubule Junctions Activate Atrial Ca2+ Release Across Species |
| Brandenburg S, Pawlowitz J, (...), Lehnart SE | Frontiers in Physiology | 2018 | | |
Marker-Free Tracking for Motion Artifact Compensation and Deformation Measurements in Optical Mapping Videos of Contracting Hearts |
| Christoph J, Luther S | Frontiers in Physiology | 2018 | | |
Follow the Light - From Low-Energy Defibrillation to Multi-Site Photostimulation |
| Diaz-Maue L, Schwaerzle M, Ruther P, Luther S, Richter C | 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) | 2018 | | |
Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors | | Dworatzek E, Mahmoodzadeh S, (...), Regitz-Zagrosek V | Cardiovascular Research | 2018 | | |
Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart |
| Dybkova N, Ahmad S, (...), Sossalla S | Cardiovascular Research | 2018 | | |
CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure |
| Gröschel C, Sasse A, (...), Dressel R | Frontiers in Immunology | 2018 | | |
The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research |
| Gross JC, Zelarayán LC | Frontiers in Cardiovascular Medicine | 2018 | | |
Energy-Reduced Arrhythmia Termination Using Global Photostimulation in Optogenetic Murine Hearts |
| Quiñonez Uribe RA, Luther S, Diaz-Maue L, Richter C | Frontiers in Physiology | 2018 | | |
Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure |
| Tampe B, Tampe D, (...), Zeisberg M | Journal of Clinical Investigation | 2018 | | |
Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytes | | El-Battrawy I, Zhao Z, (...), Akin I | International Journal of Cardiology | 2018 | | |
Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes |
| Zhao Z, Lan H, (...), Akin I | Stem Cells International | 2018 | | |
Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy | | El-Battrawy I, Zhao Z, (...), Akin I | Circulation-Genomic and Precision Medicine | 2018 | | |
miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and Cardiotoxicity | | Gupta SK, Garg A, (...), Thum T | Molecular Therapy | 2018 | | |
Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes. |
| Krysiak J, Unger A, (...), Linke WA | Nature Communications | 2018 | | |
CaosDB - Research Data Management for Complex, Changing, and Automated Research Workflows |
| Fitschen T, Schlemmer A, Hornung D, tom Wörden H, Parlitz U, Luther S | arXiv | 2018 | | |
COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis. |
| Aich A, Wang C, (...), Rehling P | eLife | 2018 | | |
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. |
| Iyer LM, Nagarajan S, (...), Zelarayán LC | Nucleic acids research | 2018 | | |
Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing |
| Long C, Li H., (...), | Science Advances | 2018 | | |
Towards optogenetic control of spatiotemporal cardiac dynamics | | Diaz-Maue L, Luther S, Richter C | Proceedings Optogenetics and Optical Manipulation | 2018 | | |
Electromechanical vortex filaments during cardiac fibrillation. |
| Christoph J, Chebbok M, (...), Luther S | Nature | 2018 | | |
Chromatin dynamics at the core of kidney fibrosis. | | Tampe B, Zeisberg M | Matrix Biology | 2018 | | |
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes. |
| Soliman K, Göttfert F, Rosewich H, Thoms S, Gärtner J | Scientific reports | 2018 | | |
Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models: focus on TASK-1 |
| Wiedmann F, Schulte JS, (...), Schmidt C | Basic Research in Cardiology | 2018 | | |
Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes |
| Cyganek L, Tiburcy M, (...), Guan K | JCI Insight | 2018 | | |
Prof Niels Voigt talks to Prof Stanley Nattel about advances in atrial fibrillation research and career insights |
| Voigt N, Nattel S | Cardiovascular Research | 2018 | | |
Dataset for article "Axial Tubule Junctions Activate Atrial Ca(2+) Release across Species" doi: 10.3389/fphys.2018.01227 |
| Brandenburg S, Pawlowitz J, Lehnart SE | Zenodo | 2018 | | |
Mutations in TOP3A Cause a Bloom Syndrome-like Disorder |
| Martin C, Sarlós K, (...), Jackson AP | American Journal of Human Genetics | 2018 | | |
Correction: Formation of COPI-coated vesicles at a glance (doi:10.1242/jcs.209890). |
| Arakel EC, Schwappach B | Journal of cell science | 2018 | | |
Wikidata as semantic representation platform of the scientific achievements of the biomedical Collaborative Research Centre 1002 |
| Suhr M, Jahn N, Mietchen D, Kusch H | German Medical Science GMS Publishing House | 2018 | | |
A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance |
| Huttner IG, Wang LW, (...), Fatkin D | Circulation-Genomic and Precision Medicine | 2018 | | |
From seamless acquisition and sustainable management to publication of next-generation sequencing data |
| Umbach N, Freckmann L, Knopp C, Meyer T, Suhr M, Kusch H | German Medical Science GMS Publishing House | 2018 | | |
High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis |
| Xu X, Tan X, (...), Zeisberg M | Nature Communications | 2018 | | |
The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease |
| Dudek J, Hartmann M, Rehling P | Biochimica et Biophysica Acta-Molecular Basis of Disease | 2018 | | |
Application of basic research data management with FAIRDOM/SEEK from a medical informatics perspective |
| Bauer CR, Knopp C, Bender T, Kusch H, Sax U | German Medical Science GMS Publishing House | 2018 | | |
PROV@TOS, a Java Wrapper To Capture Provenance for Talend Open Studio Jobs |
| Parciak M, Bauer CR, (...), Sax U | German Medical Science GMS Publishing House | 2018 | | |
Usage of persistent identifiers to implement the FAIR guiding principles in medical research data management systems |
| Knopp C, Bauer CR, Kusch H, Sax U | German Medical Science GMS Publishing House | 2018 | | |
Pilot integration of an electronic lab notebook and an open source research data repository as part of a modular biomedical research data platform |
| Kusch H, Nussbeck SY, Kiraly P, Macneil R, Crosas M | Dataverse Community Meeting 2018 | 2018 | | |
Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure |
| Fischer TH, Eiringhaus J, (...), Sossalla S | European Journal of Heart Failure | 2018 | | |
Voltage-Gated Calcium Channels and Their Roles in Cardiac Electrophysiology | | Heijman J, Molina CE, Voigt N | Cardiac and Vascular Biology | 2018 | | |
Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression |
| Mohamed BA, Hartmann N, (...), Toischer K | Science Translational Medicine | 2018 | | |
Treatments targeting inotropy |
| Maack C, Eschenhagen T, (...), Mebazaa A | European Heart Journal | 2018 | | |
German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management |
| Thomas D, Christ T, (...), Voigt N | Clinical Research in Cardiology | 2018 | | |
Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia |
| Chowdhury A, Aich A, (...), Dudek J | Cell Reports | 2018 | | |
Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome | | Paolacci S, Li Y, (...), Hennekam RC | Journal of Medical Genetics | 2018 | | |
Empagliflozin directly improves diastolic function in human heart failure |
| Pabel S, Wagner S, (...), Sossalla S | European Journal of Heart Failure | 2018 | | |
Material presented at EAHIL 2018 (Cardiff, UK) in Session CEC 7 (Electronic Laboratory Notebooks) |
| Krause E, Kusch H, Tate D | Göttingen Research Online (Data.GRO) | 2018 | | |
ESC Congress 2018 highlights in basic science: a report from the Scientists of Tomorrow |
| Schmidt C, Voigt N | Cardiovascular Research | 2018 | | |
The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy |
| Ahmad S, Tirilomis P, (...), Sossalla S | ESC Heart Failure | 2018 | | |
Multiple Localization by Functional Translational Readthrough | | Bersch K, Lobos Matthei I, Thoms S | Sub-Cellular Biochemistry | 2018 | | |
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation |
| Danielsen TK, Manotheepan R, (...), Stokke MK | PLoS One | 2018 | | |
Ryanodine receptor dysfunction and the resolution revolution: how Nobel Prize-winning techniques transform cardiovascular research |
| Voigt N, Lehnart SE | Cardiovascular Research | 2018 | | |
Titin as a force generating muscle protein under regulatory control | | Freundt JK, Linke WA | Journal of Applied Physiology | 2018 | | |
The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation |
| Singh S, Lämmle S, (...), Richter F | Scientific Reports | 2018 | | |
Agonistic and antagonistic roles of fibroblasts and cardiomyocytes on viscoelastic stiffening of engineered human myocardium |
| Schlick SF, Spreckelsen F, (...), Rehfeldt F | Progress in Biophysics and Molecular Biology | 2018 | | |
Hallermann-Streiff syndrome: A missing molecular link for a highly recognizable syndrome | | Schmidt J, Wollnik B | American Journal of Medical Genetics Part C-Seminars in Medical Genetics | 2018 | | |
Digital Notebooks - Productivity Tools For Researchers - Event Materials |
| Adams R, Branchett S, (...), Therier J | Zenodo | 2018 | | |
The Use of Glycosylation Tags as Reporters for Protein Entry into the Endoplasmic Reticulum in Yeast and Mammalian Cells. | | Buentzel J, Thoms S | Methods in Molecular Biology | 2017 | | |
P1334 - The relevant role of SR Ca leak in the development of heart failure |
| Mohamed BA, Kattner L, (...), Toischer K | European Journal of Heart Failure | 2017 | | |
P41 - Studying beta-adrenergic signalling in a patient-specific induced pluripotent stem cell model for Takotsubo syndrome |
| Hübscher D, Borchert T, (...), Streckfuß-Bömeke K | European Journal of Heart Failure | 2017 | | |
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling |
| Abilez OJ, Tzatzalos E, (...), Wu JC | Stem Cells | 2017 | | |
Dietary spermidine for lowering high blood pressure |
| Eisenberg T, Abdellatif M, (...), Madeo F | Autophagy | 2017 | | |
Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D |
| Gröschel C, Hübscher D, (...), Dressel R | Frontiers in Immunology | 2017 | | |
Titin Gene and Protein Functions in Passive and Active Muscle | | Linke WA | Annual Review of Physiology | 2017 | | |
Collaboration of Heat Shock Protein 70 and Stress-induced NKG2D Ligands in the Activation of NK Cells against Tumors | | Dressel R | Current Immunology Reviews | 2017 | | |
The contractile adaption to preload depends on the amount of afterload |
| Schotola H, Sossalla ST, (...), Toischer K | ESC Heart Failure | 2017 | | |
Translating Myocardial Remuscularization. |
| Zimmermann WH | Circulation research | 2017 | | |
Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy. |
| Hofhuis J, Bersch K, (...), Thoms S | Journal of cell science | 2017 | | |
Defined Engineered Human Myocardium with Advanced Maturation for Applications in Heart Failure Modelling and Repair. |
| Tiburcy M, Hudson JE, (...), Zimmermann WH | Circulation | 2017 | | |
Remuscularization of the failing heart. |
| Zimmermann WH | Journal of Physiology-London | 2017 | | |
A protocol for registration and correction of multicolour STED superresolution images. |
| Hebisch E, Wagner E, Westphal V, Sieber JJ, Lehnart SE | Journal of microscopy | 2017 | | |
Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity. | | Neef S, Heijman J, (...), El-Armouche A | Naunyn-Schmiedebergs Archives of Pharmacology | 2017 | | |
Vortices Termination in the Cardiac Muscle | | Krinsky VI, Biktashev VN, Otani NF, Luther S | Nonlinear Systems and Complexity; Advances in Dynamics, Patterns, Cognition | 2017 | | |
Mechanisms of vortices termination in the cardiac muscle. |
| Hornung D, Biktashev VN, (...), Luther S | Royal Society Open Science | 2017 | | |
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure. |
| Schmidt C, Wiedmann F, (...), Thomas D | Progress in biophysics and molecular biology | 2017 | | |
Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue. |
| Boccia E, Luther S, Parlitz U | Philosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences | 2017 | | |
Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure. |
| Dewenter M, Neef S, (...), El-Armouche A | Circulation-Heart Failure | 2017 | | |
PDE2 at the crossway between cAMP and cGMP signalling in the heart. | | Weber S, Zeller M, Guan K, Wunder F, Wagner M, El-Armouche A | Cellular Signalling | 2017 | | |
Engineered Heart Repair | | Fujita B, Zimmermann WH | Clinical Pharmacology and Therapeutics | 2017 | | |
Myocardial Tissue Engineering for Regenerative Applications. |
| Fujita B, Zimmermann WH | Current Cardiology Reports | 2017 | | |
Generation of a KLF15 homozygous knockout human embryonic stem cell line using paired CRISPR/Cas9n, and human cardiomyocytes derivation |
| Noack C, Haupt LP, Zimmermann WH, Streckfuß-Bömeke K, Zelarayán LC | Stem Cell Research | 2017 | | |
Opinion paper: Data provenance challenges in biomedical research : it - Information Technology | | Baum B, Bauer CR, (...), Sax U | IT-Information Technology | 2017 | | |
P4479 - B-catenin/TCF7L2 signaling orchestrates initiation of pathological hypertrophic cardiac remodeling by inducing chromatin modifications |
| Iyer LM, Noack C, (...), Zelarayán LC | European Heart Journal | 2017 | | |
P2545 - Inducible paracrine release of IGF-1 improves heart muscle thickness and function |
| Soong PL, Sur S, (...), Zimmermann WH | European Heart Journal | 2017 | | |
5044 - Heat shock protein 47 knockout in fibroblasts causes contractile dysfunction in engineered human myocardium |
| Sur S, Noack C, (...), Zimmermann WH | European Heart Journal | 2017 | | |
P5841 - PP1 activation as novel antiarrhythmic approach in human heart failure |
| Eiringhaus J, Fischer TH, (...), Sossalla ST | European Heart Journal | 2017 | | |
Cardiac optogenetics: using light to monitor cardiac physiology. |
| Koopman CD, Zimmermann WH, Knöpfel T, de Boer TP | Basic research in cardiology | 2017 | | |
Technical Aspects of Data Provenance in Clinical Trials |
| Parciak M, Bauer CR, Baum B, Kusch H, Sax U | German Medical Science GMS Publishing House | 2017 | | |
Towards sustainable research data management in advanced light microscopy |
| Henke C, Kusch H, Marzec B, Nussbeck SY, Umbach N | German Medical Science GMS Publishing House | 2017 | | |
Emergent dynamics of spatio-temporal chaos in a heterogeneous excitable medium | | Bitthin P, Berg S, Parlitz U, Luther S | Chaos | 2017 | | |
State-of-the-Art in Tissue-Engineered Heart Repair | | Fujita B, Tiburcy M, Ensminger S, Zimmermann WH | Cardiac Regeneration | 2017 | | |
Complex restitution behavior and reentry in a cardiac tissue model for neonatal mice. |
| Mayer A, Bittihn P, Luther S | Physiological reports | 2017 | | |
Role of Cardiolipin in Mitochondrial Signaling Pathways. |
| Dudek J | Frontiers in cell and developmental biology | 2017 | | |
Electromechanical optical mapping. |
| Christoph J, Schröder-Schetelig J, Luther S | Progress in biophysics and molecular biology | 2017 | | |
Functional correction of dystrophin actin binding domain mutations by genome editing. |
| Kyrychenko V, Kyrychenko S, (...), Olson EN | JCI Insight | 2017 | | |
Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes. |
| Streckfuß-Bömeke K, Tiburcy M, (...), Guan K | Journal of Molecular and Cellular Cardiology | 2017 | | |
Cardiomyocyte proliferation prevents failure in pressure overload but not volume overload. |
| Toischer K, Zhu W, (...), Hasenfuß G | Journal of Clinical Investigation | 2017 | | |
De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. |
| Ehmke N, Graul-Neumann L, (...), Kornak U | American journal of human genetics | 2017 | | |
Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4. |
| Perera RK, Fischer TH, (...), Nikolaev VO | Scientific reports | 2017 | | |
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. |
| Richter KN, Revelo NH, (...), Rizzoli SO | EMBO journal | 2017 | | |
T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure. |
| Gröschel C, Sasse A, (...), Dressel R | Scientific reports | 2017 | | |
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development | | Gordon CT, Xue S, (...), Reversade B | Nature Genetics | 2017 | | |
Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes. |
| Hamdani N, Herwig M, Linke WA | Biophysical Reviews | 2017 | | |
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy. |
| Borchert T, Hübscher D, (...), Streckfuß-Bömeke K | Journal of the American College of Cardiology | 2017 | | |
The Tumorigenicity of Multipotent Adult Germline Stem Cells Transplanted into the Heart Is Affected by Natural Killer Cells and by Cyclosporine A Independent of Its Immunosuppressive Effects. |
| Hübscher D, Kaiser D, Elsner L, Monecke S, Dressel R, Guan K | Frontiers in immunology | 2017 | | |
Immunological Properties of Murine Parthenogenetic Stem Cell-Derived Cardiomyocytes and Engineered Heart Muscle |
| Didié M, Galla S, Muppala V, Dressel R, Zimmermann WH | Frontiers in Immunology | 2017 | | |
Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation Products |
| Johannsen H, Muppala V, (...), Dressel R | Frontiers in Immunology | 2017 | | |
Dataset for: Complex restitution behavior and reentry in a cardiac tissue model for neonatal mice |
| Mayer A, Bittihn P, Luther S | Figshare | 2017 | | |
Supplementary material from "Mechanisms of vortices termination in the cardiac muscle" |
| Hornung D, Biktashev VN, (...), Luther S | Figshare | 2017 | | |
A new defibrillation mechanism: Termination of reentrant waves by propagating action potentials induced by nearby heterogeneities |
| Han S, Otani NF, Krinski V, Luther S | Computing in Cardiology Conference (CinC) | 2016 | | |
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code |
| Hofhuis J, Schueren F, (...), Thoms S | Open Biology | 2016 | | |
Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice |
| Gogiraju R, Schroeter MR, (...), Schäfer K | Cardiovascular Research | 2016 | | |
Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes | | Hartmann N, Pabel S, (...), Sossalla S | Heart Rhythm | 2016 | | |
Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury–to–chronic kidney disease progression | | Tampe B, Steinle U, (...), Zeisberg M | Kidney International | 2016 | | |
Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction |
| Vettel C, Lindner M, (...), El-Armouche A | Circulation Research | 2016 | | |
Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury | | Ott C, Martens H, (...), Ehrenreich H | Molecular Medicine | 2016 | | |
hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities |
| Veerman CC, Mengarelli I, (...), Bezzina CR | Scientific Reports | 2016 | | |
Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention | | Chowdhury SK, Liu W, (...), Wang X | Circulation | 2016 | | |
Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective method | | Liu X, Qi J, Xu X, Zeisberg M, Guan K, Zeisberg EM | Differentiation | 2016 | | |
Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure. |
| Fischer TH, Herting J, (...), Sossalla S | Europace | 2016 | | |
Strip and Dress the Human Heart |
| Zimmermann WH | Circulation Research | 2016 | | |
A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1. |
| Kilisch M, Lytovchenko O, Arakel EC, Bertinetti D, Schwappach B | Journal of Cell Science | 2016 | | |
Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome. |
| Dudek J, Cheng IF, (...), Rehling P | EMBO molecular medicine | 2016 | | |
The molecular and functional identities of atrial cardiomyocytes in health and disease. |
| Brandenburg S, Arakel EC, Schwappach B, Lehnart SE | Biochimica et Biophysica Acta-Molecular Cell Research | 2016 | | |
Long-Term Oocyte-Like Cell Development in Cultures Derived from Neonatal Marmoset Monkey Ovary. |
| Fereydouni B, Salinas-Riester G, (...), Behr R | Stem Cells International | 2016 | | |
The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA. |
| Isernhagen A, Schilling D, (...), Dressel R | Immunogenetics | 2016 | | |
Bifurcations, chaos, and sensitivity to parameter variations in the Sato cardiac cell model |
| Ottea S, Berg S, Luther S, Parlitz U | Communications in Nonlinear Science and Numerical Simulation | 2016 | | |
Inhibition of CaMKII Attenuates Progressing Disruption of Ca2+ Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure. | | Fischer TH, Kleinwächter A, (...), Sossalla S | Artificial Organs | 2016 | | |
DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition. |
| Tan X, Xu X, Zeisberg M, Zeisberg EM | PLoS One | 2016 | | |
High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation. | | Tan X, Xu X, Zeisberg EM, Zeisberg M | Biochemical and Biophysical Research Communications | 2016 | | |
The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology. | | Hartmann N, Mason FE, (...), Sossalla S | Journal of Molecular and Cellular Cardiology | 2016 | | |
The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine. | | Mason FE, Sossalla S | Journal of Cardiovascular Pharmacology and Therapeutics | 2016 | | |
"Reduced" Coumarin Dyes with an O-Phosphorylated 2,2-Dimethyl-4-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline Fragment: Synthesis, Spectra, and STED Microscopy. | | Nizamov S, Sednev MV, (...), Hell SW | Chemistry-A European Journal | 2016 | | |
The transcriptomes of novel marmoset monkey embryonic stem cell lines reflect distinct genomic features. |
| Debowski K, Drummer C, (...), Behr R | Scientific Reports | 2016 | | |
Isolation and Primary Culture of Adult Mouse Cardiac Fibroblasts |
| Zafeiriou MP, Noack C, Zelarayán LC | Bio-Protocol | 2016 | | |
Axial tubule junctions control rapid calcium signaling in atria. |
| Brandenburg S, Kohl T, (...), Lehnart SE | Journal of Clinical Investigation | 2016 | | |
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles |
| Qin X, Riegler J, (...), Wu JC | Circulation-Cardiovascular Imaging | 2016 | | |
Cardioprotection and lifespan extension by the natural polyamine spermidine. | | Eisenberg T, Abdellatif M, (...), Madeo F | Nature Medicine | 2016 | | |
Titin-truncating variants affect heart function in disease cohorts and the general population. |
| Schafer S, de Marvao A, (...), Cook SA | Nature Genetics | 2016 | | |
Optogenetic Light Crafting Tools for the Control of Cardiac Arrhythmias. | | Richter C, Christoph J, Lehnart SE, Luther S | Methods in Molecular Biology | 2016 | | |
Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release. |
| Manotheepan R, Danielsen TK, (...), Stokke MK | Cardiovascular Research | 2016 | | |
Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET. |
| Sprenger JU, Bork NI, Herting J, Fischer TH, Nikolaev VO | PLoS One | 2016 | | |
Spontaneous Termination of Reentrant Activity under Myocardial Acute Ischemia: Role of Cellular Conductivity and its Relation to Ischemic Heterogeneities |
| Boccia E, Parlitz U, Luther S | Communications in Nonlinear Science and Numerical Simulation | 2016 | | |
Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks. |
| Isernhagen A, Malzahn D, Bickeböller H, Dressel R | Frontiers in Immunology | 2016 | | |
Scanning and resetting the phase of a pinned spiral wave using periodic far field pulses |
| Shajahan TK, Berg S, Luther S, Krinski V, Bittihn P | New Journal of Physics | 2016 | | |
Erratum to: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury |
| Ott C, Martens H, (...), Ehrenreich H | Molecular Medicine | 2016 | | |
Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo. |
| Rivera-Monroy J, Musiol L, (...), Vilardi F | Scientific reports | 2016 | | |
Generation of human induced pluripotent stem cells using non-synthetic mRNA. |
| Rohani L, Fabian C, (...), Stolzing A | Stem cell research | 2016 | | |
Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice. |
| Gogiraju R, Xu X, (...), Schäfer K | Journal of the American Heart Association | 2015 | | |
Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy. |
| Perera RK, Sprenger JU, (...), Nikolaev VO | Circulation research | 2015 | | |
Entropy Rate Maps of Complex Excitable Dynamics in Cardiac Monolayers |
| Schlemmer A, Berg S., Shajahan TK, Luther S, Parlitz U | Entropy | 2015 | | |
Sensing Cardiac Electrical Activity With a Cardiac Myocyte Targeted Optogenetic Voltage Indicator. |
| Chang Liao ML, de Boer T, (...), Zimmermann WH | Circulation research | 2015 | | |
Basin structure of optimization based state and parameter estimation | | Schumann-Bischoff J, Parlitz U, (...), Luther S | Chaos | 2015 | | |
Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation. | | Godier-Furnémont AF, Tiburcy M, (...), Zimmermann WH | Biomaterials | 2015 | | |
I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model |
| Friedrich FW, Sotoud H, (...), El-Armouche A | IJC Heart & Vasculature | 2015 | | |
Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2. |
| Zaglia T, Pianca N, (...), Mongillo M | Proceedings of the National Academy of Sciences of the United States of America | 2015 | | |
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. |
| Hinson JT, Chopra A, (...), Seidman CE | Science | 2015 | | |
Metadata capture in an electronic notebook: How to make it as simple as possible? |
| Menzel J, Weil P, Nussbeck SY | GMS Medizinische Informatik, Biometrie und Epidemiologie | 2015 | | |
Mechanical stimulation in the engineering of heart muscle. | | Liaw NY, Zimmermann WH | Advanced Drug Delivery Reviews | 2015 | | |
Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model. |
| Riegler J, Tiburcy M, (...), Wu JC | Circulation research | 2015 | | |
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. | | Sharma P, Abbasi C, (...), Gramolini AO | Nature Communications | 2015 | | |
Stabilization of three-dimensional scroll waves and suppression of spatiotemporal chaos by heterogeneities | | Spreckelsen F, Hornung D, Steinbock O, Parlitz U, Luther S | Physical Review E | 2015 | | |
Tracking of Inhaled Near-Infrared Fluorescent Nanoparticles in Lungs of SKH-1 Mice with Allergic Airway Inflammation. | | Markus MA, Napp J, (...), Alves F | ACS nano | 2015 | | |
On the Adjacency Matrix of RyR2 Cluster Structures. |
| Walker MA, Kohl T, Lehnart SE, Greenstein JL, Lederer WJ, Winslow RL | PLoS computational biology | 2015 | | |
Molecular and structural transition mechanisms in long-term volume overload. |
| Mohamed BA, Schnelle M, (...), Toischer K | European journal of heart failure | 2015 | | |
In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease. |
| Sprenger JU, Perera RK, (...), Nikolaev VO | Nature Communications | 2015 | | |
Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII. |
| Fischer TH, Herting J, (...), Sossalla S | Cardiovascular Research | 2015 | | |
Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1. |
| Meijer van Putten RM, Mengarelli I, (...), Wilders R | Frontiers in physiology | 2015 | | |
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1. |
| Kruse V, Hamann C, (...), Dressel R | PLoS One | 2015 | | |
Ca(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKII. |
| Johnston AS, Lehnart SE, Burgoyne JR | Frontiers in Pharmacology | 2015 | | |
Intensity matters: Ryanodine receptor regulation during exercise. |
| Kohl T, Weninger G, Zalk R, Eaton P, Lehnart SE | Proceedings of the National Academy of Sciences of the United States of America | 2015 | | |
Association of circulating angiogenesis inhibitors and asymmetric dimethyl arginine with coronary plaque burden. |
| Charytan DM, Cinelli A, Zeisberg EM | Fibrogenesis & tissue repair | 2015 | | |
Association of activated vitamin D use with myocardial fibrosis and capillary supply: results of an autopsy study. |
| Charytan DM, Padera RF, Helfand AM, Zeisberg EM | Renal Failure | 2015 | | |
Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. |
| Xu X, Friehs I, (...), Zeisberg EM | Circulation research | 2015 | | |
Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis. |
| Xu X, Tan X, (...), Zeisberg EM | Cardiovascular Research | 2015 | | |
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease. |
| Hartmann S, Ridley AJ, Lutz S | Frontiers in Pharmacology | 2015 | | |
p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts. | | Ongherth A, Pasch S, (...), Lutz S | Journal of Molecular and Cellular Cardiology | 2015 | | |
RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes. |
| Jatho A, Hartmann S, (...), Lutz S | PLoS One | 2015 | | |
Crosstalk of cardiomyocytes and fibroblasts in co-cultures. |
| Rother J, Richter C, (...), Tarantola M | Open Biology | 2015 | | |
Changes of sleep-stage transitions due to ageing and sleep disorder. |
| Schlemmer A, Parlitz U, Luther S, Wessel N, Penzel T | Philosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences | 2015 | | |
Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. |
| Debowski K, Warthemann R, (...), Behr R | PLoS One | 2015 | | |
The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation. |
| Isernhagen A, Malzahn D, (...), Dressel R | EMBO molecular medicine | 2015 | | |
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload. |
| Montes-Cobos E, Li X, (...), Reichardt HM | PLoS One | 2015 | | |
Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting. |
| Xu X, Smorag L, (...), Pantakani DV | Nature Communications | 2015 | | |
Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. |
| Pacheu-Grau D, Bareth B, (...), Deckers M | Cell metabolism | 2015 | | |
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane. |
| Pfaff J, Monroy JR, (...), Kehlenbach RH | Journal of cell science | 2015 | | |
Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C. |
| Amanzada A, Reinhardt L, Fey D, Zeisberg EM, Mihm S | PLoS One | 2015 | | |
Datenorganisation eines klinischen Sonderforschungsbereiches in einer integrierten, langfristig verfügbaren Forschungsdatenplattform |
| Kusch H, Schmitt O, Marzec B, Nussbeck SY, | German Medical Science GMS Publishing House | 2015 | | |
Quantifying spatiotemporal complexity of cardiac dynamics using ordinal patterns | | Schlemmer A, Berg S, Shajahan TK, Luther S, Parlitz U, | 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) | 2015 | | |
S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding |
| Alegre-Cebollada J, Kosuri P, (...), | Cell | 2014 | | |
Ins Herz des sekretorischen Pfades: Stress mobilisiert Ionenkanäle |
| Arakel EC, Schwappach B, | BIOspektrum | 2014 | | |
Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes |
| Arakel EC, Brandenburg S, (...), | Journal of Cell Science | 2014 | | |
Emerging importance of oxidative stress in regulating striated muscle elasticity |
| Beckendorf L, Linke WA, | Journal of Muscle Research and Cell Motility | 2014 | | |
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase | | Belge C, Hammond J, (...), | Circulation | 2014 | | |
Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease |
| Charytan DM, Padera R, (...), | International Journal of Cardiology | 2014 | | |
Aim24 stabilizes respiratory chain supercomplexes and is required for efficient respiration |
| Deckers M, Balleininger M, (...), | FEBS letters | 2014 | | |
The Janus face of BNP therapy in chronic heart failure: beneficial effects unmasked by β blockers? | | Dewenter M, Vettel V, El-Armouche A, | Heart | 2014 | | |
Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa |
| Dybkova N, Wagner S, (...), | Cardiovascular Research | 2014 | | |
Ca(2+) /calmodulin-dependent protein kinase II equally induces sarcoplasmic reticulum Ca(2+) leak in human ischaemic and dilated cardiomyopathy | | Fischer TH, Eiringhaus J, (...), | European Journal of Heart Failure | 2014 | | |
Herzinsuffizienz: "From Bench to Bedside" - Neues im Bereich der Ionenhomöostase | | Förster A, Maier LS, | Journal für Kardiologie | 2014 | | |
Transgenic Mice for Real-Time Visualization of cGMP in Intact Adult Cardiomyocytes | | Götz KR, Sprenger JU, (...), | Circulation Research | 2014 | | |
Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology | | Köhler AC, Sag CM, Maier LS | Journal of Molecular and Cellular Cardiology | 2014 | | |
Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins |
| Kötter S, Unger A, (...), | Journal of Cell Biology | 2014 | | |
Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy | | Kreusser MM, Lehmann LH, (...), | Circulation | 2014 | | |
Gigantic business: titin properties and function through thick and thin | | Linke WA, Hamdani N | Circulation Research | 2014 | | |
Experimental antiarrhythmic targets: CaMKII inhibition - ready for clinical evaluation? | | Maier LS, | Current Medicinal Chemistry | 2014 | | |
CaMKII regulation of cardiac K channels |
| Mustroph J, Maier LS, Wagner S, | Frontiers in Pharmacology | 2014 | | |
Paradoxical Effects on Force Generation after Efficient β1-Adrenoceptor Knockdown in Reconstituted Heart Tissue | | Neuber C, Müller OJ, (...), El-Armouche A | Journal of Pharmacology and Experimental Therapeutics | 2014 | | |
The laboratory notebook in the 21st century |
| Nussbeck SY, Weil P, (...), | EMBO reports | 2014 | | |
Detecting synchronization and interrelations in multivariate time series | | Parlitz U, Luther S, | 2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) | 2014 | | |
Local observability of state variables and parameters in nonlinear modeling quantified by delay reconstruction | | Parlitz U, Schumann-Bischoff J, Luther S | Chaos | 2014 | | |
Quantifying uncertainty in state and parameter estimation | | Parlitz U, Schumann-Bischoff J, Luther S, | Physical Review E | 2014 | | |
Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner | | Sag CM, Mallwitz A, (...), | Journal of Molecular and Cellular Cardiology | 2014 | | |
Evaluation of machine learning methods for the long-term prediction of cardiac diseases | | Schlemmer A, Zwirnmann H, Zabel M, Parlitz U, Luther S, | 2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) | 2014 | | |
Eliminating pinned spiral waves in cardiac monolayer by far field pacing | | Shajahan TK, Krinski VI, Knyazeva S, Luther S, | 2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) | 2014 | | |
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes | | Slimane ZH, Bedioune I, (...), | Cardiovascular Research | 2014 | | |
Effects of ranolazine on torsades de pointes tachycardias in a healthy isolated rabbit heart model |
| Sossalla S, Wallisch N, (...), | Cardiovascular Therapeutics | 2014 | | |
Induction of Tet3-dependent epigenetic remodeling by low-dose Hydralazine attenuates progression of chronic kidney disease |
| Tampe B, Tampe D, (...), | EBioMedicine | 2014 | | |
Collagen-Based Engineered Heart Muscle | | Tiburcy M, Meyer T, Soong PL, Zimmermann WH, | Methods in molecular biology | 2014 | | |
Modeling myocardial growth and hypertrophy in engineered heart muscle | | Tiburcy M, Zimmermann WH, | Trends in Cardiovascular Medicine | 2014 | | |
Dopamine and Lipophilic Derivates Protect Cardiomyocytes against Cold Preservation Injury | | Vettel C, Hottenrott MC, (...), | Journal of Pharmacology and Experimental Therapeutics | 2014 | | |
PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways | | Vettel C, Lämmle S, (...), | American Journal of Physiology-Heart and Circulatory Physiology | 2014 | | |
Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function |
| Voelkel T, Andresen C, (...), | Biochimica et Biophysica Acta-Molecular Cell Research | 2014 | | |
Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles |
| Wagner E, Brandenburg S, Kohl T, Lehnart SE, | Journal of Visualized Experiments | 2014 | | |
NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII | | Wagner S, Dantz C, (...), | Journal of Molecular and Cellular Cardiology | 2014 | | |
Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177 |
| Walther S, Pluteanu F, (...), | American Journal of Physiology-Heart and Circulatory Physiology | 2014 | | |
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling | | Wright PT, Nikolaev VO, (...), | Journal of Molecular and Cellular Cardiology | 2014 | | |
Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction | | Zafiriou MP, Noack C, (...), Zelarayán LC | Stem Cells | 2014 | | |
Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure |
| Zeisberg M, Tampe B, (...), | American Journal of Pathology | 2014 | | |
Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. |
| Tampe B, Tampe D, (...), Zeisberg M | Journal of the American Society of Nephrology | 2014 | | |
Lights on for HIF-1α: genetically enhanced mouse cardiomyocytes for heart tissue imaging. |
| Hesse AR, Levent E, Zieseniss A, Tiburcy M, Zimmermann WH, Katschinski DM | Cellular Physiology and Biochemistry | 2014 | | |
miR-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction. |
| Izarra A, Moscoso I, (...), Bernad A | Stem Cell Reports | 2014 | | |
Minimierung des Dokumentationsaufwandes für die medizinische Grundlagenforschung mithilfe eines elektronischen Laborbuches: Aufgezeigt am Beispiel eines Western Blot Metadatenschemata |
| Menzel J, Weil, P, Nussbeck SY, | German Medical Science GMS Publishing House | 2014 | | |
Anbindung eines elektronischen Laborbuchs an eine vorhandene Langzeitarchivierungsinfrastruktur |
| Marzec B, Weil P, Nussbeck SY, | German Medical Science GMS Publishing House | 2014 | | |
Integrierte Portalumgebung und verteilte Echtzeitsuche für medizinische Langzeitarchivierung |
| Schmitt O, Weil P, Wieder P, Nussbeck SY, | German Medical Science GMS Publishing House | 2014 | | |
Cardiac Progenitor Cells and their Therapeutic Application for Cardiac Repair |
| Cyganek L, Chen S, Borchert T, Guan K, | Journal of Clinical & Experimental Cardiology | 2013 | | |
Parthenogenetic stem cells for tissue-engineered heart repair |
| Didie M, Christalla P, (...), | Journal of Clinical Investigation | 2013 | | |
Preservation of left ventricular function and morphology in volume-loaded versus volume-unloaded heterotopic heart transplants | | Didie M, Biermann D, (...), | American Journal of Physiology-Heart and Circulatory Physiology | 2013 | | |
Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome |
| Dudek J, Cheng IF, (...), | Stem Cell Research | 2013 | | |
Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathology | | Fischer TH, Herting J, (...), | Circulation | 2013 | | |
The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies? |
| Fischer TH, Neef S, Maier LS, | Journal of Molecular and Cellular Cardiology | 2013 | | |
The ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisis |
| Fischer TH, Maier LS, Sossalla S, | Heart Failure Reviews | 2013 | | |
Advances and techniques to measure cGMP in intact cardiomyocytes | | Götz KR, Nikolaev VO, | Methods in Molecular Biology | 2013 | | |
Archivierung von Genomdaten |
| Grütz R, Mathieu N, Löhnhardt B, Weil P, Krawczak M, | Medizinische Genetik | 2013 | | |
Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction |
| Hamdani N, Bishu KG, von Frieling-Salewsky M, Redfield MM, Linke WA, | Cardiovascular Research | 2013 | | |
Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation | | Hamdani N, Krysiak J, (...), | Circulation Research | 2013 | | |
Special issue "Novel perspectives on heart failure" |
| Hasenfuß G, Heusch G | Basic Research in Cardiology | 2013 | | |
Function and regulation of serine/threonine phosphatases in the healthy and diseased heart | | Heijman J, Dewenter M, El-Armouche A, Dobrev D, | Journal of Molecular and Cellular Cardiology | 2013 | | |
Imaging T-tubules: dynamic membrane structures for deep functions |
| Kohl T, Lehnart SE, | Cardiovascular Research | 2013 | | |
Superresolution microscopy in heart - cardiac nanoscopy |
| Kohl T, Westphal V, Hell SW, Lehnart SE | Journal of Molecular and Cellular Cardiology | 2013 | | |
Understanding the physiology of heart failure through cellular and in vivo models-towards targeting of complex mechanisms |
| Lehnart SE, | Experimental Physiology | 2013 | | |
RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study |
| Maier LS, Layug B, (...), | JACC-Heart failure | 2013 | | |
The late Na current as a therapeutic target: where are we? | | Maier LS, Sossalla S, | Journal of Molecular and Cellular Cardiology | 2013 | | |
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes | | Mehel H, Emons J, (...), | Journal of the American College of Cardiology | 2013 | | |
Requirement analysis for an electronic laboratory notebook for sustainable data management in biomedical research | | Menzel J, Weil P, (...), | Studies in Health Technology and Informatics | 2013 | | |
Novel aspects of excitation-contraction coupling in heart failure | | Neef S, Maier LS, | Basic Research in Cardiology | 2013 | | |
While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice | | Neef S, Sag CM, (...), | Journal of Molecular and Cellular Cardiology | 2013 | | |
Compartmentation of cAMP signalling in cardiomyocytes in health and disease | | Perera RK, Nikolaev VO, | Acta Physiologica | 2013 | | |
Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation |
| Purohit A, Rokita AG, (...), | Circulation | 2013 | | |
The four and a half LIM-domain 2 controls early cardiac cell commitment and expansion via regulating β-catenin-dependent transcription |
| Renger A, Zafiriou MP, (...), | Stem Cells | 2013 | | |
Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII |
| Sag CM, Wolff HA, (...), | Basic Research in Cardiology | 2013 | | |
Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes | | Sag CM, Wagner S, Maier LS, | Free Radical Biology and Medicine | 2013 | | |
Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading |
| Schwoerer AP, Neef S, (...), | Pflugers Archiv-European Journal of Physiology | 2013 | | |
Ranolazine maintained sinus rhythm in a patient with refractory symptomatic atrial fibrillation |
| Sossalla S, Sohns C, (...), | Cardiovascular Therapeutics | 2013 | | |
Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approaches | | Sotoud H, Gribbon P, (...), | Journal of Biomolecular Screening | 2013 | | |
Biophysical Techniques for Detection of cAMP and cGMP in Living Cells |
| Sprenger JU, Nikolaev VO, | International Journal of Molecular Sciences | 2013 | | |
Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts |
| Streckfuß-Bömeke K, Wolf F, (...), | European Heart Journal | 2013 | | |
Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease | | Toischer K, Hartmann N, (...), | Journal of Molecular and Cellular Cardiology | 2013 | | |
Redox regulation of sodium and calcium handling | | Wagner S, Rokita AG, Anderson ME, Maier LS, | Antioxidants & Redox Signaling | 2013 | | |
Small conductance Ca-activated K channel: Small but powerful proarrhythmogenic? | | Wagner S, Maier LS, | Heart Rhythm | 2013 | | |
Patching the Heart Cardiac Repair From Within and Outside | | Ye L, Zimmermann WH, Garry DJ, Zhang J, | Circulation Research | 2013 | | |
The role of promoter hypermethylation in fibroblast activation and fibrogenesis |
| Zeisberg EM, Zeisberg M, | Journal of Pathology | 2013 | | |
Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair |
| Zimmermann WH, | Stem Cell Research & Therapy | 2013 | | |
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. |
| Luo M, Guan X, (...), Anderson ME | Journal of Clinical Investigation | 2013 | | |
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. |
| Abonnenc M, Nabeebaccus AA, (...), Mayr M | Circulation research | 2013 | | |
Nonlinear system identification employing automatic differentiation | | Schumann-Bischoff J, Luther S, Parlitz U | Communications in Nonlinear Science and Numerical Simulation | 2013 | | |
Vorbereitungsprozess für die elektronische Dokumentation und Nachnutzbarkeit von FD in ELN |
| Marzec B, Weil P, Nussbeck SY, | German Medical Science GMS Publishing House | 2013 | | |
New Treatment Options for Late Na Current, Arrhythmias, and Diastolic Dysfunction |
| Maier LS, | Current Heart Failure Reports | 2012 | | |
Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction |
| Wagner E, Lauterbach MA, (...), | Circulation Research | 2012 | | |