Published Data Registry

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TitleAuthorsJournalPublication year
DOI
PMID
Systematic and quantitative analysis of stop codon readthrough in Rett syndrome nonsense mutations(Open Access) Lebeda D, Fierenz A, Werfel L, Rosin-Arbesfeld R, Hofhuis J, Thoms SJournal of Molecular Medicine-JMM2024
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function(Open Access) Gersch S, Lange T, (...), Toischer KClinical Research in Cardiology2024
3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes(Open Access) Pochechueva TV, Schwenzer N, (...), Lehnart SEInternational Journal of Molecular Sciences2024
Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions(Open Access) Bloothooft M, Verbruggen B, Seibertz F, Heyden MAGvd, Voigt N, de Boer TPFrontiers in Physiology2024
Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak(Open Access) Dewenter M, Seitz T, (...), Neef SESC Heart Failure2024
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathyWali R, Xu H, (...), Ebert ABiological Chemistry2024
Microtubules: highway to … arrhythmia?Liutkute A, Prosser BL, Voigt NCardiovasc Res2024
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts(Open Access) Foo B, Amedei H, (...), Lehnart SEbioRxiv2024
Through the Haze: Unveiling the Link Between Smoking and Atrial FibrillationMason FE, Voigt NAmerican Journal of Physiology-Heart and Circulatory Physiology2024
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling(Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LCCommunications Biology2024
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implicationsBode D, Pronto JRD, Schiattarella GG, Voigt NNature Reviews Cardiology2024
The importance of DNA sequence for nucleosome positioning in transcriptional regulation(Open Access) Sahrhage M, Paul NB, Beißbarth T, Haubrock MLife Science Alliance2024
Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresisSchröder S, Epple R, Fischer A, Schettler VJJTherapeutic Apheresis and Dialysis2024
Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function(Open Access) Falcão‐Pires I, Ferreira AF, (...), Tocchetti CGEuropean Journal of Heart Failure2024
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation(Open Access) Fakuade FE, Hubricht D, (...), Voigt NCirculation2024
Patients with paradoxical low-flow, low-gradient aortic stenosis gain the least benefit from TAVI among all hemodynamic subtypes(Open Access) Puls M, Beuthner BE, (...), Hasenfuß GClinical Research in Cardiology2024
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study(Open Access) Talevi V, Melas K, (...), Breteler MMJournal of Translational Medicine2024
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome(Open Access) Busley AV, Gutiérrez-Gutiérrez O, (...), Cyganek LCell Reports2024
Dysferlin Enables Tubular Membrane Proliferation in Cardiac HypertrophyPaulke NJ, Fleischhacker C, (...), Brandenburg SCirculation Research2024
Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation(Open Access) Kim R, Nagel SH, Liaw NY, Zimmermann W, Zelarayán LC, Schoger EStem Cell Research2024
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes(Open Access) Amedei H, Paul NB, (...), Lenz CFrontiers in Analytical Science2024
Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatmentXu X, Tan X, (...), Hasenfuß GCardiovascular Research2024
Blood‐derived microRNAs are related to cognitive domains in the general population(Open Access) Melas K, Talevi V, (...), Breteler MMBAlzheimers & Dementia2024
Circulating microRNAs are related to cognitive domains in the general population(Open Access) Melas K, Talevi V, (...), Breteler MMmedRxiv2024
Towards sustainable research data management of longitudinal, heterogeneous data from cardiac tissue engineering(Open Access) Smolorz SA, Dittrich GM, (...), Kusch HGerman Medical Science GMS Publishing House2024
Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness(Open Access) Haertter D, Hauke L, Driehorst T, Nishi K, Zimmermann W, Schmidt CFbioRxiv2024
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts(Open Access) Ruiz-Orera J, Miller DC, (...), Hübner NNature Cardiovascular Research2024
Cardiac arrhythmias: the growing role of autoantibodies in diagnosis and treatment(Open Access) Fakuade FE, Grune J, Voigt NEuropean Heart Journal2024
The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites(Open Access) Zung N, Aravindan N, (...), Schuldiner MbioRxiv2024
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes(Open Access) Amedei H, Paul N, (...), Lenz CbioRxiv2024
Addressing SARS-CoV-2 viroporins with antiarrhythmic drugs(Open Access) Bloothooft M, Voigt N, de Boer TPEuropace2024
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts(Open Access) Foo B, Amedei H, (...), Lehnart SEPLoS One2024
Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes(Open Access) Paasche A, Wiedmann F, (...), Schmidt CBasic Research in Cardiology2024
Mapping Hierarchical File Structures to Semantic Data Models for Efficient Data Integration into Research Data Management Systems(Open Access) tom Wörden H, Spreckelsen F, Luther S, Parlitz U, Schlemmer AData2024
High throughput methods for cardiac cellular electrophysiology studies: The road to personalized medicineSeibertz F, Voigt NAmerican Journal of Physiology-Heart and Circulatory Physiology2024
Epicardial adipose tissue as an independent predictor of long-term outcome in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement(Open Access) Schulz A, Beuthner BE, (...), Schuster AClinical Research in Cardiology2024
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants(Open Access) Knauer C, Haltern H, (...), Cyganek LMolecular Therapy-Nucleic Acids2024
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fractionGotthardt M, Lehnart SECardiovascular Research2024
USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration(Open Access) Prokakis E, Bamahmoud H, (...), Wegwitz FCell Communication and Signaling2024
Tissue-specific roles of peroxisomes revealed by expression meta-analysis(Open Access) Plessner M, Thiele L, Hofhuis J, Thoms SBiology Direct2024
Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement(Open Access) Beuthner BE, Elkenani M, (...), Toischer KESC Heart Failure2024
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy(Open Access) Schwenzer N, Tsukanov R, (...), Lehnart SEbioRxiv2024
The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation(Open Access) Pikunov AV, Syunyaev RA, (...), Efimov IRbioRxiv2023
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes(Open Access) Weber F, Klas S, (...), Cyganek LSocial Science Research Network2023
Approaching automation of multiple instance orchestration of the menoci web portal(Open Access) Freckmann L, Henke C, (...), Kusch HGerman Medical Science GMS Publishing House2023
Author Correction: Selective optogenetic control of Gq signaling using human NeuropsinWagdi A, Malan D, (...), Bruegmann TNature Communications2023
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling(Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LCCommunications Biology2023
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome(Open Access) Busley AV, Gutiérrez-Gutiérrez Ó, (...), Cyganek LbioRxiv2023
GBA/GBN-position on the feedback of incidental findings in biobank-based research: consensus-based workflow for hospital-based biobanks(Open Access) Geiger J, Fuchs J, (...), Jahns REuropean Journal of Human Genetics2023
Defective COX1 expression in aging mice liver(Open Access) Witte S, Boshnakovska A, Özdemir M, Chowdhury A, Rehling P, Aich ABiology Open2023
Optical mapping of contracting hearts(Open Access) Kappadan V, Sohi A, (...), Ng FSThe Journal of Physiology2023
DNA Methylation Analysis Identifies Novel Epigenetic Loci in Dilated Murine Heart upon Exposure to Volume Overload(Open Access) Xu X, Elkenani M, (...), Mohamed BAInternational Journal of Molecular Sciences2023
The history-dependent features of muscle force production: A challenge to the cross-bridge theory and their functional implicationsHahn D, Han S, Joumaa VJournal of Biomechanics2023
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart(Open Access) Nanadikar MS, Vergel Leon AM, (...), Katschinski DMNature Communications2023
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V(Open Access) Viktoria Busley A, Kleinsorge M, Cyganek LStem Cell Research2023
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V(Open Access) Busley AV, Cyganek LStem Cell Research2023
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in CardiomyocytesDai Y, Ignatyeva N, (...), Ebert ACirculation Research2023
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues(Open Access) Nakhaei-Rad S, Haghighi F, (...), Ahmadian MRCommunications Biology2023
Molecular and Functional Relevance of NaV1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model(Open Access) Hartmann N, Knierim M, (...), Streckfuss-Bömeke KInternational Journal of Molecular Sciences2023
Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC)(Open Access) Priesmeier L, Schoger E, Cyganek L, Cecilia Zelarayán LStem Cell Research2023
Vicious Twins: RyR2 Dysfunction and Structural RemodelingVoigt N, Seibertz F, Fakuade FECirculation Research2023
Live-Cell Imaging of Peroxisomal Calcium Levels and DynamicsSargsyan Y, Thoms SMethods Mol Biol2023
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome(Open Access) Chowdhury A, Boshnakovska A, (...), Rehling PEMBO Molecular Medicine2023
Mapping hierarchical file structures to semantic data models for efficient data integration into research data management systems(Open Access) Tom Wörden H, Spreckelsen F, Luther S, Parlitz U, Schlemmer APreprints2023
Bioengineering of a human innervated cardiac muscle model(Open Access) Schneider LV, Bao G, (...), Zafeiriou MbioRxiv2023
Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine(Open Access) Mustroph J, Baier MJ, (...), Neef SCirculation2023
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development(Open Access) Seibertz F, Rubio T, (...), Voigt NCardiovascular Research2023
RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer(Open Access) Prokakis E, Jansari S, (...), Wegwitz FCell Death & Disease2023
4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applications(Open Access) Goodarzi Hosseinabadi H, Biswas A, (...), Ionov LSmall2023
Metabolomic Profiling in Patients with Different Hemodynamic Subtypes of Severe Aortic Valve Stenosis(Open Access) Bengel P, Elkenani M, (...), Schnelle MBiomolecules2023
Aortic valve calcification and myocardial fibrosis determine outcome following transcatheter aortic valve replacement(Open Access) Evertz R, Hub S, (...), Schuster AESC Heart Failure2023
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs(Open Access) Shi R, Reichardt M, (...), Brügmann TCardiovascular Research2023
Titin governs myocardial passive stiffness with major support from microtubules and actin and the extracellular matrix(Open Access) Loescher CM, Freundt JK, (...), Linke WANature Cardiovascular Research2023
Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome(Open Access) Kutschka I, Bertero E, (...), Dudek JBasic Research in Cardiology2023
Regulatory roles of the N6-methyladenosine demethylase FTO in cardiac remodeling(Open Access) Annamalai K, Buchholz E, Castro R, Panyam N, Fischer A, Toischer KEuropean Heart Journal2023
Approaching automation of multiple instance orchestration of the menoci web portal(Open Access) Freckmann L, Henke C, (...), Kusch HBausteine Forschungsdatenmanagement2023
A dual-targeted drug inhibits cardiac ryanodine receptor Ca<sup>2+</sup>leak but activates SERCA2a Ca<sup>2+</sup>uptake(Open Access) Wegener JW, Mitronova GY, (...), Lehnart SELife Science Alliance2023
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy(Open Access) Kyriakopoulou E, Versteeg D, (...), van Rooij ENature Cardiovascular Research2023
Dissolution of spiral wave’s core using cardiac optogenetics(Open Access) Hussaini S, Lädke SL, (...), Luther SPLOS Computational Biology2023
Enlightening Cardiac Arrhythmia with OptogeneticsBruegmann T, Boyle PM, Schneider-Warme FHeart Rate and Rhythm2023
Titin takes centerstage among cytoskeletal contributions to myocardial passive stiffness(Open Access) Loescher CM, Linke WACytoskeleton2023
Protocol to develop force-generating human skeletal muscle organoids(Open Access) Shahriyari M, Rinn M, Hofemeier AD, Babych A, Zimmermann W, Tiburcy MSTAR Protocols2023
Implications for neutrophils in cardiac arrhythmiasHegemann N, Barth L, Doering Y, Voigt N, Grune JAmerican Journal of Physiology-Heart and Circulatory Physiology2023
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine(Open Access) Schoger E, Lelek S, Panáková D, Zelarayán LCFrontiers in Cardiovascular Medicine2022
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells(Open Access) Pavez-Giani MG, Cyganek LFrontiers in Cell and Developmental Biology2022
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes(Open Access) Brandenburg S, Pawlowitz J, (...), Lehnart SEJournal of Molecular and Cellular Cardiology2022
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells(Open Access) Oleksiievets N, Sargsyan Y, (...), Tsukanov RCommunications Biology2022
Human–Device Interaction in the Life Science LaboratorySöldner R, Rheinländer S, Meyer T, Olszowy M, Austerjost JAdvances in Biochemical Engineering-Biotechnology2022
Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration(Open Access) Li W, Luo X, (...), Schubert MPharmaceuticals2022
Modulatorische Einheiten bei Herzinsuffizienz(Open Access) Hasenfuß G, Kaul A, Lehnart SE, Linke WA, Zelarayán LC, Zimmermann WDer Kardiologe2022
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease(Open Access) Shomroni O, Sitte M, (...), Salinas GScientific Reports2022
Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation(Open Access) Hartmann N, Preuß L, (...), Toischer KESC Heart Failure2022
Selective optogenetic control of Gq signaling using human Neuropsin(Open Access) Wagdi A, Malan D, (...), Bruegmann TNature Communications2022
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation – A proof-of-concept studyJebran A, Tiburcy M, (...), Zimmermann WJournal of Molecular and Cellular Cardiology2022
The Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular Disease(Open Access) Zschüntzsch J, Meyer S, (...), Tiburcy MCells2022
Herzinsuffizienz(Open Access) Herting J, Fischer TH, Maack CNephrologe2022
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathyJung P, Seibertz F, (...), Voigt NBasic Research in Cardiology2022
IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress(Open Access) Nanadikar M, Leon AV, (...), Katschinski DResearchsquare2022
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart RepairTiburcy M, Meyer T, Satin P, Zimmermann WMethods in Molecular Biology2022
Background calcium influx in arrhythmia: lead actor or extra?(Open Access) Fakuade FE, Fauconnier J, Voigt NJournal of Physiology-London2022
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes(Open Access) Weninger G, Pochechueva T, (...), Lehnart SEScientific Reports2022
Not the classical serendipity: does doxapram treat atrial fibrillation?Liutkute A, Brundel BJJM, Voigt NCardiovasc Res2022
Remote control of the heart and beyondZimmermann WScience2022
Effects of Atrial Fibrillation on the Human Ventricle(Open Access) Pabel S, Knierim M, (...), Sossalla SCirculation Research2022
A Mathematical Model for Electrical Activity in Pig Atrial Tissue(Open Access) Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder RFrontiers in Physiology2022
RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes(Open Access) Levay MK, Krobert KA, (...), Wieland TBasic Research in Cardiology2022
Spatiotemporal Organization of Electromechanical Phase Singularities during High-Frequency Cardiac Arrhythmias(Open Access) Molavi Tabrizi A, Mesgarnejad A, Bazzi M, Luther S, Christoph J, Karma APhysical Review X2022
Hemodynamic stress‐induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein(Open Access) Mohamed BA, Elkenani M, (...), Toischer KJournal of Cellular and Molecular Medicine2022
A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming(Open Access) Lyra-Leite DM, Gutiérrez-Gutiérrez O, Wang M, Zhou Y, Cyganek L, Burridge PWSTAR Protocols2022
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis(Open Access) Brandenburg S, Otto L, (...), Lehnart SEJournal of Molecular and Cellular Cardiology2022
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes(Open Access) Seibertz F, Rapedius M, (...), Voigt NCommunications Biology2022
Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study(Open Access) Lange T, Backhaus SJ, (...), Schuster AJournal of Cardiovascular Magnetic Resonance2022
There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments(Open Access) Rapedius M, Obergrussberger A, (...), Fertig NFrontiers in Molecular Neuroscience2022
Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling(Open Access) Paulke N, Amlaz S, (...), Brandenburg SEuropean Heart Journal2022
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy(Open Access) Shahriyari M, Islam MR, (...), Tiburcy MJournal of Cachexia Sarcopenia and Muscle2022
Titin force in muscle cells alters lattice order, thick and thin filament protein formationHessel AL, Ma W, (...), Linke WAProceedings of the National Academy of Sciences of the United States of America2022
Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissuesSantos GL, DeGrave AN, (...), Lutz SBiomaterials Advances2022
Calcium in peroxisomes: An essential messenger in an essential cell organelle(Open Access) Sargsyan Y, Kalinowski J, Thoms SFrontiers in Cell and Developmental Biology2022
Editorial: Cardiac optogenetics: Using light to observe and excite the heart(Open Access) Bruegmann T, Smith GL, Lehnart SEFrontiers in Physiology2022
Targeting Mitochondrial Calcium Handling to Treat Atrial FibrillationVoigt N, Maack C, Pronto JRDJournal of the American College of Cardiology2022
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp(Open Access) Rosholm KR, Badone B, (...), Bell DCFrontiers in Molecular Neuroscience2022
An optimized protocol for the enrichment of small vesicles from murine and non-human primate heart tissue(Open Access) Bleckwedel F, Germena G, Hinkel R, Zelarayán LCTrillium extracellular vesicles2022
Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs(Open Access) Nakhaei-Rad S, Bazgir F, (...), Ahmadian MRbioRxiv2022
NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overloadSchnelle M, Sawyer I, (...), Shah AMCardiovascular Research2021
Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast InteractionsZimmermann WCirculation Research2021
5.3 Kollaboratives Arbeiten mit Daten(Open Access) Engelhardt C, Kusch HPraxishandbuch Forschungsdatenmanagement2021
Online Supplemental Files for "Caveolin3 Stabilizes McT1-mediated Lactate/Proton Transport in Cardiomyocytes"(Open Access) Lehnart SEGöttingen Research Online (Data.GRO)2021
Epigenetic gene expression links heart failure to memory impairment(Open Access) Islam MR, Lbik D, (...), Fischer AEMBO Molecular Medicine2021
Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes(Open Access) Peper J, Kownatzki-Danger D, (...), Lehnart SECirculation Research2021
Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition(Open Access) Hakroush S, Kopp SB, (...), Tampe BFrontiers in Immunology2021
Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes(Open Access) Kittana N, Assali M, (...), Lutz SInternational Journal of Nanomedicine2021
Monitoring mitochondrial translation in living cells(Open Access) Yousefi R, Fornasiero EF, (...), Pacheu‐Grau DEMBO reports2021
Sustainable Deployment of Research Infrastructure Components(Open Access) Bender T, Parciak M, Suhr M, Sax U, Bauer CRGerman Medical Science GMS Publishing House2021
Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm controlHoffmann S, Schmitteckert S, (...), Rappold GBiochimica et Biophysica Acta-Gene Regulatory Mechanisms2021
RhoGEF17 - An Essential Regulator of Endothelial Cell Death and Growth(Open Access) Weber P, Baltus D, (...), Lutz SCells2021
Predicting the duration of chaotic transients in excitable media(Open Access) Aron M, Lilienkamp T, Luther S, Parlitz UJournal of Physics-Complexity2021
cAMP Imaging at Ryanodine Receptors Reveals β2-Adrenoceptor Driven Arrhythmias(Open Access) Berisha F, Götz K, (...), Nikolaev VOCirculation Research2021
Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7 ‐related osteopetrosis(Open Access) Rössler U, Hennig AF, (...), Kornak UJournal of Bone and Mineral Research2021
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci(Open Access) Kyryachenko S, Georges A, (...), Bouatia-Naji NCirculation Research2021
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state(Open Access) Yigit G, Sheffer R, (...), Brockmann KJournal of Medical Genetics2021
Unraveling the mysteries of the titin–N2A signalosome(Open Access) Hessel AL, Linke WAJournal of General Physiology2021
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation(Open Access) Sadredini M, Haugsten Hansen M, (...), Stokke MKAmerican Journal of Physiology-Heart and Circulatory Physiology2021
TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes(Open Access) Sattler K, El-Battrawy I, (...), Akin IScientific Reports2021
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression(Open Access) Schoger E, Zimmermann W, Cyganek L, Zelarayán LCStem Cell Research2021
Organs-on-chip models for cardiovascular drug development(Open Access) Zimmermann WCardiovascular Research2021
Fibroblast Derived Human Engineered Connective Tissue for Screening ApplicationsSantos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz SJournal of Visualized Experiments2021
Management of Metadata Types in Basic Cardiological Research(Open Access) Kusch H, Kossen R, (...), Nussbeck SYStudies in Health Technology and Informatics2021
Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice(Open Access) Chen Y, Lüttmann FF, (...), Braun TScience2021
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1.(Open Access) Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MKPhysiological Reports2021
Biallelic variants in YRDC cause a developmental disorder with progeroid features(Open Access) Schmidt J, Goergens J, (...), Wollnik BHuman Genetics2021
GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072(Open Access) Kusch H, Bauer CR, (...), Sax UGöttingen Research Online (Data.GRO)2021
Pulsed low-energy stimulation initiates electric turbulence in cardiac tissue(Open Access) Majumder R, Hussaini S, Zykov VS, Luther S, Bodenschatz EPLOS Computational Biology2021
A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease(Open Access) Shomroni O, Sitte M, (...), Salinas GResearchsquare2021
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy(Open Access) Bertero E, Nickel A, (...), Maack CCirculation2021
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutationsFomin A, Gärtner A, (...), Linke WAScience Translational Medicine2021
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure(Open Access) Bengel P, Dybkova N, (...), Sossalla SNature Communications2021
Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: From molecular mechanisms to therapeutic targets(Open Access) Boer RA, Heymans S, (...), Thum TEuropean Journal of Heart Failure2021
Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity(Open Access) Shahriyari M, Islam MR, (...), Tiburcy MbioRxiv2021
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation(Open Access) Schoger E, Zimmermann W, Cyganek L, Zelarayán LCStem Cell Research2021
The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool(Open Access) Wegener JW, Wagdi A, (...), Lehnart SEFrontiers in Physiology2021
Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice(Open Access) Zheng X, Zhang L, (...), Doeppner TRTranslational Stroke Research2021
Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy(Open Access) Yigit G, Wollnik BMedizinische Genetik2021
Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells(Open Access) Sargsyan Y, Bickmeyer U, Gibhardt CS, Streckfuss-Bömeke K, Bogeski I, Thoms SLife Science Alliance2021
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy(Open Access) Xu H, Wali R, (...), Ebert AFEBS Letters2021
Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation(Open Access) Fakuade FE, Steckmeister V, (...), Voigt NCardiovascular Research2020
Troponin destabilization impairs sarcomere-cytoskeleton interactions in iPSC-derived cardiomyocytes from dilated cardiomyopathy patients(Open Access) Dai Y, Amenov A, (...), Ebert AScientific Reports2020
Epigenetic gene-expression links heart failure to memory impairment(Open Access) Islam R, Lbik D, (...), Fischer AbioRxiv2020
COA6 facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria(Open Access) Pacheu-Grau D, Wasilewski M, (...), Rehling RJournal of Molecular Biology2020
Interdisciplinary Research on Aortic Valve Stenosis: a Longitudinal Collection of Biospecimens and Clinical Data of Patients Undergoing Transcatheter Aortic Valve Replacement(Open Access) Beuthner BEC, Topci R, (...), Nussbeck SYOpen Journal of Bioresources2020
Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis(Open Access) Puls M, Beuthner BE, (...), Hasenfuß GEuropean Heart Journal2020
menoci: Lightweight Extensible Web Portal enabling FAIR Data Management for Biomedical Research Projects(Open Access) Suhr M, Lehmann C, (...), Nußbeck SYarXiv2020
Tissue Engineered Heart Repair from Preclinical Models to First-in-Patient StudiesZimmermann WCurrent Opinion in Physiology2020
Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon(Open Access) Zambusi A, Burhan ÖP, Di Giaimo R, Schmid B, Ninkovic JCells2020
Functions of Vertebrate FerlinsBulankina AV, Thoms SCells2020
Inhibition of NaV1.8 Prevents Atrial Arrhythmogenesis in Human and Mice(Open Access) Pabel S, Ahmad S, (...), Sossalla SBasic Research in Cardiology2020
CRISPLD1: a novel conserved target in the transition to human heart failure(Open Access) Khadjeh S, Hindmarsh V, (...), Hasenfuss GBasic Research in Cardiology2020
Excitable Dynamics in Neural and Cardiac SystemsBarrio R, Coombes S, Desroches M, Fenton F, Luther S, Pueyo ECommunications in Nonlinear Science and Numerical Simulation2020
Guidelines for a Standardized File Structure for Scientific Data(Open Access) Spreckelsen F, Rüchardt B, Lebert J, Luther S, Parlitz U, Schlemmer APreprints2020
Guidelines for a Standardized Filesystem Layout for Scientific Data(Open Access) Spreckelsen F, Rüchardt B, Lebert J, Luther S, Parlitz U, Schlemmer AData2020
Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice(Open Access) Zheng X, Zhang L, (...), Doeppner TRTranslational Stroke Research2020
Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy(Open Access) Zschüntzsch J, Jouvenal PV, (...), Schmidt JJournal of Cachexia Sarcopenia and Muscle2020
Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes(Open Access) Kleinsorge M, Cyganek LSTAR Protocols2020
Generation of Engineered Human Myocardium in a Multi-well Format(Open Access) Tiburcy M, Meyer T, Liaw NY, Zimmermann WSTAR Protocols2020
Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice(Open Access) Rudolph F, Fink C, (...), Gotthardt MNature Communications2020
Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis(Open Access) Backhaus SJ, Lange T, (...), Schuster AJournal of Cardiovascular Magnetic Resonance2020
Dysferlin links excitation–contraction coupling to structure and maintenance of the cardiac transverse–axial tubule systemHofhuis J, Bersch K, (...), Thoms SEuropace2020
Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome-Associated CardiomyopathyHanses U, Kleinsorge M, (...), Cyganek LCirculation2020
Loss of SPEG Inhibitory Phosphorylation of RyR2 Promotes Atrial FibrillationCampbell HM, Quick AP, (...), Wehrens XHCirculation2020
Sacubitrilat reduces pro‐arrhythmogenic sarcoplasmic reticulum Ca2+ leak in human ventricular cardiomyocytes of patients with end‐stage heart failure(Open Access) Eiringhaus J, Wünsche CM, (...), Fischer THESC Heart Failure2020
Insights into latest cardiovascular research at scientific institutions in Göttingen and Heidelberg: a report by the ESC Scientists of Tomorrow(Open Access) Schmidt C, Voigt NCardiovascular Research2020
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids(Open Access) Zafeiriou M, Bao G, (...), Zimmermann WNature Communications2020
Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation(Open Access) Schoger E, Argyriou L, Cyganek L, Zelarayán LCStem Cell Research2020
IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency(Open Access) Luo X, Li W, (...), Guan KFrontiers in Cell and Developmental Biology2020
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholambanMenzel J, Kownatzki-Danger D, (...), Schwappach BScience Signaling2020
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin(Open Access) Swist S, Unger A, (...), Linke WANature Communications2020
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxideMontiel V, Bella R, (...), Balligand JScience Translational Medicine2020
Inhibition of Prolyl-Hydroxylase Domain Enzymes Protects From Reoxygenation Injury in Engineered Human MyocardiumLevent E, Noack C, Zelarayán LC, Katschinski DM, Zimmermann W, Tiburcy MCirculation2020
Alexa, do science! Voice-activated assistants hit the lab bench(Open Access) Perkel JMNature2020
Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine(Open Access) Pan Z, Ebert A, Liang PPflugers Archiv-European Journal of Physiology2020
Menoci: lightweight extensible web portal enhancing data management for biomedical research projects(Open Access) Suhr M, Lehmann C, (...), Nussbeck SYBMC Bioinformatics2020
Cellular and mitochondrial mechanisms of atrial fibrillation(Open Access) Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt NBasic Research in Cardiology2020
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control(Open Access) Rathjens FS, Blenkle A, (...), Zafeiriou MCardiovascular Research2020
Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis(Open Access) Ganapathi M, Argyriou L, (...), Wollnik BHuman Genetics2020
Local translation in synaptic mitochondria influences synaptic transmission(Open Access) Yousefi R, Fornasiero EF, (...), Pacheu-Grau DbioRxiv2020
Connexin hemichannels in atrial fibrillation: orphaned and irrelevant?(Open Access) Fakuade FE, Tomsits P, Voigt NCardiovascular Research2020
Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium CurrentTomsits P, Schüttler D, Kääb S, Clauss S, Voigt NJournal of Visualized Experiments2020
CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect(Open Access) Reil JC, Reil GH, (...), Hamdani NJournal of Physiology-London2020
Integrated Ca2+ flux and AFM force analysis in human iPSC-derived cardiomyocytesMalkovskiy AV, Ignatyeva N, Dai Y, Hasenfuss G, Rajadas J, Ebert ABiological Chemistry2020
Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling(Open Access) Eiringhaus J, Herting J, (...), Fischer THBasic Research in Cardiology2019
ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure(Open Access) Madonna R, Van Laake LW, (...), Sluijter JPGCardiovascular Research2019
O2 affects mitochondrial functionality ex vivo(Open Access) Nanadikar MS, Vergel Leon AM, (...), Katschinski DMRedox Biology2019
Cardiac macrotissues-on-a-plate models for phenotypic drug screensMeyer T, Tiburcy M, Zimmermann WAdvanced Drug Delivery Reviews2019
N-glycosylation-dependent regulation of hK2P17.1 currents(Open Access) Wiedmann F, Schlund D, (...), Schmidt CMolecular Biology of the Cell2019
Posttranslational modifications of titin from cardiac muscle: how, where and what for?(Open Access) Koser F, Loescher C, Linke WAFEBS Journal2019
Optogenetic Monitoring of the Glutathione Redox State in Engineered Human Myocardium(Open Access) Trautsch I, Heta E, (...), Zimmermann WFrontiers in Physiology2019
Engineered Heart Tissue Models from hiPSC-Derived Cardiomyocytes and Cardiac ECM for Disease Modeling and Drug Testing ApplicationsGoldfracht I, Efraim Y, (...), Gepstein LActa Biomaterialia2019
Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis(Open Access) Brandenburg S, Pawlowitz J, (...), Lehnart SEJCI Insight2019
Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes(Open Access) Ebert A, Joshi AU, (...), Wu JCCirculation Research2019
Drug Testing in Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1Zhao Z, Li X, (...), Borggrefe MClinical Pharmacology and Therapeutics2019
The Translational Landscape of the Human Heartvan Heesch S, Witte F, (...), Hubner NCell2019
The Ways of Tails: the GET Pathway and moreBorgese N, Coy-Vergara J, Colombo SF, Schwappach BProtein Journal2019
CaosDB—Research Data Management for Complex, Changing, and Automated Research Workflows(Open Access) Fitschen T, Schlemmer A, Hornung D, tom Wörden H, Parlitz U, Luther SData2019
Simultaneous unpinning of multiple vortices in two-dimensional excitable media(Open Access) tom Wörden H, Parlitz U, Luther SPhysical Review E2019
Workshop on data management costs and efforts, 28 May 2019 in Göttingen(Open Access) Roertgen S, Kusch H, (...), Ebert BGöttingen Research Online (Data.GRO)2019
Scientists on the Spot: Autophagy and heart disease(Open Access) Voigt N, Sadoshima JCardiovascular Research2019
Genetic deletion of calcium/calmodulin-dependent protein kinase type II delta does not mitigate adverse myocardial remodeling in volume-overloaded hearts(Open Access) Mohamed BA, Elkenani M, (...), Toischer KScientific Reports2019
Assessing the role of extracellular signal‐regulated kinases 1 and 2 in volume overload‐induced cardiac remodelling(Open Access) Jochmann S, Elkenani M, (...), Schnelle MESC Heart Failure2019
KLF15-Wnt–Dependent Cardiac Reprogramming Up-Regulates SHISA3 in the Mammalian Heart(Open Access) Noack C, Iyer LM, (...), Zelarayán LCJournal of the American College of Cardiology2019
Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere FunctionZaunbrecher RJ, Abel AN, (...), Murry CECirculation2019
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial FibrillationAlsina KM, Hulsurkar M, (...), Wehrens XHCirculation2019
A trap mutant reveals the physiological client spectrum of TRC40(Open Access) Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach BJournal of Cell Science2019
Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues(Open Access) Santos GL, Hartmann S, Zimmermann W, Ridley A, Lutz SJournal of Molecular and Cellular Cardiology2019
Cardiac Tissue Engineering as Use Case to Connect Biomedical Research Laboratories to an Emerging Global Data Infrastructure(Open Access) Suhr M, Umbach N, Meyer T, Zimmermann WH, Sax UStudies in Health Technology and Informatics2019
Arzneimittelinteraktionen, die man kennen muss!(Open Access) Voigt N, Ort K, Sossalla SFortschritte der Neurologie Psychiatrie2019
Blut und Urin Begleitschein(Open Access) Nußbeck SGöttingen Research Online (Data.GRO)2019
Protokoll Myokardbiopsien(Open Access) Nußbeck SGöttingen Research Online (Data.GRO)2019
Protokoll Blut- und Uringewinnung und -verarbeitung(Open Access) Nußbeck SGöttingen Research Online (Data.GRO)2019
Spiral wave unpinning facilitated by wave emitting sites in cardiac monolayersPunacha S, Berg S, Sebastian A, Krinski VI, Luther S, Shajahan TKProceedings of the Royal Society A-Mathematical Physical and Engineering Sciences2019
Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish(Open Access) Burczyk MS, Burkhalter MD, (...), Philipp MJCI Insight2019
P1235 Acetylcholine-activated inward-rectifier potassium currents in atrial cardiomyocytes derived from induced pluripotent stem cells and atrial engineered heart muscle preparationsSpringer R, Seibertz F, (...), Voigt NEuropean Heart Journal2019
P1621 m6A RNA-methylation in the progression of heart failureBuchholz E, Berulava T, (...), Toischer KEuropean Heart Journal2019
P5998 The Phosphodiesterase 4D interacting protein averts volume overload - but not pressure overload-induced pathological myocardial remodelingMohamed BA, Elkenani M, Jakubiczka-Smorag J, Bader M, Hasenfuß G, Toischer KEuropean Heart Journal2019
P3829 Antiarrhythmic effects of Sacubitrilat (LBQ657) on Ca2+ homeostasis in ventricular cardiomyocytesEiringhaus J, Wuensche C, Herting J, Hasenfuß G, Sossalla S, Fischer TEuropean Heart Journal2019
1180 Cardiomyocyte-specific deletion of Brd4 induces hypertrophic cardiomyopathy and suggests a novel function for the chromatin reader as co-repressor in the healthy heartLbik D, Buchholz E, Mohamed B, Fischer A, Hasenfuß G, Toischer KEuropean Heart Journal2019
Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes(Open Access) Sattler K, El-Battrawy I, (...), Akin IScientific Reports2019
A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytesEl-Battrawy I, Albers S, (...), Akin IEuropace2019
A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods(Open Access) Hübscher D, Rebs S, (...), Streckfuß-Bömeke KStem Cells International2019
CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart(Open Access) Schoger E, Carroll KJ, (...), Zelarayán LCCirculation Research2019
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation(Open Access) Berulava T, Buchholz E, (...), Toischer KEuropean Journal of Heart Failure2019
51Cr-release to monitor NK cell cytotoxicityElsner L, Dressel RMethods in Enzymology2019
Staying in Healthy Contact: How Peroxisomes Interact with Other Cell OrganellesSargsyan Y, Thoms STrends in Molecular Medicine2019
Leaving spreadsheets behind – FAIR documentation and representation of human stem cell lines in the Collaborative Research Centre 1002(Open Access) Lehmann C, Suhr M, (...), Kusch HGerman Medical Science GMS Publishing House2019
Towards standardized documentation of mouse lines in biomedical basic research(Open Access) Rheinländer S, Aschenbrandt G, Nussbeck SY, Suhr M, Kusch HGerman Medical Science GMS Publishing House2019
Regeneration competent satellite cell niches in rat engineered skeletal muscle(Open Access) Tiburcy M, Markov A, (...), Zimmermann WFASEB BioAdvances2019
Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1Antunes D, Chowdhury A, (...), Rapaport DJournal of Molecular Medicine-JMM2019
Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling(Open Access) Gogiraju R, Hubert A, (...), Schäfer KCirculation-Heart Failure2019
Arzneimittelinteraktionen, die man kennen muss!Voigt N, Ort K, Sossalla SDeutsche Medizinische Wochenschrift2019
Posters presented at "Workshop zu Forschungsdatenmanagement und -infrastruktur in DFG-Sonderforschungsbereichen", 26./27. November 2018 in Göttingen(Open Access) Roertgen S, Kusch H, (...), Schwandt SGöttingen Research Online (Data.GRO)2019
Presentations and material of "Workshop zu Forschungsdatenmanagement und -infrastruktur in DFG-Sonderforschungsbereichen", 26./27. November 2018 in Göttingen(Open Access) Roertgen S, Kusch H, (...), Schwandt SGöttingen Research Online (Data.GRO)2019
Monitoring Real-Time Cyclic Nucleotide Dynamics in Subcellular MicrodomainsBastug Z, Nikolaev VOCyclic Nucleotide Signaling2018
Modeling Short QT Syndrome Using Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes(Open Access) El‐Battrawy I, Lan H, (...), Akin IJournal of the American Heart Association2018
Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathyEl-Battrawy I, Zhao Z, (...), Akin IEuropace2018
P2835 Low-energy control of spatiotemporal cardiac dynamics using structured photo-stimulation(Open Access) Quinonez Uribe RA, Luther S, Richter CEuropean Heart Journal2018
Axial Tubule Junctions Activate Atrial Ca2+ Release Across Species(Open Access) Brandenburg S, Pawlowitz J, (...), Lehnart SEFrontiers in Physiology2018
Marker-Free Tracking for Motion Artifact Compensation and Deformation Measurements in Optical Mapping Videos of Contracting Hearts(Open Access) Christoph J, Luther SFrontiers in Physiology2018
Follow the Light - From Low-Energy Defibrillation to Multi-Site Photostimulation(Open Access) Diaz-Maue L, Schwaerzle M, Ruther P, Luther S, Richter C2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)2018
Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptorsDworatzek E, Mahmoodzadeh S, (...), Regitz-Zagrosek VCardiovascular Research2018
Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart(Open Access) Dybkova N, Ahmad S, (...), Sossalla SCardiovascular Research2018
CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure(Open Access) Gröschel C, Sasse A, (...), Dressel RFrontiers in Immunology2018
The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research(Open Access) Gross JC, Zelarayán LCFrontiers in Cardiovascular Medicine2018
Energy-Reduced Arrhythmia Termination Using Global Photostimulation in Optogenetic Murine Hearts(Open Access) Quiñonez Uribe RA, Luther S, Diaz-Maue L, Richter CFrontiers in Physiology2018
Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure(Open Access) Tampe B, Tampe D, (...), Zeisberg MJournal of Clinical Investigation2018
Estradiol protection against toxic effects of catecholamine on electrical properties in human-induced pluripotent stem cell derived cardiomyocytesEl-Battrawy I, Zhao Z, (...), Akin IInternational Journal of Cardiology2018
Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes(Open Access) Zhao Z, Lan H, (...), Akin IStem Cells International2018
Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular DystrophyEl-Battrawy I, Zhao Z, (...), Akin ICirculation-Genomic and Precision Medicine2018
miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and CardiotoxicityGupta SK, Garg A, (...), Thum TMolecular Therapy2018
Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.(Open Access) Krysiak J, Unger A, (...), Linke WANature Communications2018
CaosDB - Research Data Management for Complex, Changing, and Automated Research Workflows(Open Access) Fitschen T, Schlemmer A, Hornung D, tom Wörden H, Parlitz U, Luther SarXiv2018
COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.(Open Access) Aich A, Wang C, (...), Rehling PeLife2018
A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.(Open Access) Iyer LM, Nagarajan S, (...), Zelarayán LCNucleic acids research2018
Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing(Open Access) Long C, Li H., (...), Science Advances2018
Towards optogenetic control of spatiotemporal cardiac dynamicsDiaz-Maue L, Luther S, Richter CProceedings Optogenetics and Optical Manipulation2018
Electromechanical vortex filaments during cardiac fibrillation.(Open Access) Christoph J, Chebbok M, (...), Luther SNature2018
Chromatin dynamics at the core of kidney fibrosis.Tampe B, Zeisberg MMatrix Biology2018
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes.(Open Access) Soliman K, Göttfert F, Rosewich H, Thoms S, Gärtner JScientific reports2018
Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models: focus on TASK-1(Open Access) Wiedmann F, Schulte JS, (...), Schmidt CBasic Research in Cardiology2018
Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes(Open Access) Cyganek L, Tiburcy M, (...), Guan KJCI Insight2018
Prof Niels Voigt talks to Prof Stanley Nattel about advances in atrial fibrillation research and career insights(Open Access) Voigt N, Nattel SCardiovascular Research2018
Dataset for article "Axial Tubule Junctions Activate Atrial Ca(2+) Release across Species" doi: 10.3389/fphys.2018.01227(Open Access) Brandenburg S, Pawlowitz J, Lehnart SEZenodo2018
Mutations in TOP3A Cause a Bloom Syndrome-like Disorder(Open Access) Martin C, Sarlós K, (...), Jackson APAmerican Journal of Human Genetics2018
Correction: Formation of COPI-coated vesicles at a glance (doi:10.1242/jcs.209890).(Open Access) Arakel EC, Schwappach BJournal of cell science2018
Wikidata as semantic representation platform of the scientific achievements of the biomedical Collaborative Research Centre 1002(Open Access) Suhr M, Jahn N, Mietchen D, Kusch HGerman Medical Science GMS Publishing House2018
A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance(Open Access) Huttner IG, Wang LW, (...), Fatkin DCirculation-Genomic and Precision Medicine2018
From seamless acquisition and sustainable management to publication of next-generation sequencing data(Open Access) Umbach N, Freckmann L, Knopp C, Meyer T, Suhr M, Kusch HGerman Medical Science GMS Publishing House2018
High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis(Open Access) Xu X, Tan X, (...), Zeisberg MNature Communications2018
The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease(Open Access) Dudek J, Hartmann M, Rehling PBiochimica et Biophysica Acta-Molecular Basis of Disease2018
Application of basic research data management with FAIRDOM/SEEK from a medical informatics perspective(Open Access) Bauer CR, Knopp C, Bender T, Kusch H, Sax UGerman Medical Science GMS Publishing House2018
PROV@TOS, a Java Wrapper To Capture Provenance for Talend Open Studio Jobs(Open Access) Parciak M, Bauer CR, (...), Sax UGerman Medical Science GMS Publishing House2018
Usage of persistent identifiers to implement the FAIR guiding principles in medical research data management systems(Open Access) Knopp C, Bauer CR, Kusch H, Sax UGerman Medical Science GMS Publishing House2018
Pilot integration of an electronic lab notebook and an open source research data repository as part of a modular biomedical research data platform(Open Access) Kusch H, Nussbeck SY, Kiraly P, Macneil R, Crosas MDataverse Community Meeting 20182018
Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure(Open Access) Fischer TH, Eiringhaus J, (...), Sossalla SEuropean Journal of Heart Failure2018
Voltage-Gated Calcium Channels and Their Roles in Cardiac ElectrophysiologyHeijman J, Molina CE, Voigt NCardiac and Vascular Biology2018
Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression(Open Access) Mohamed BA, Hartmann N, (...), Toischer KScience Translational Medicine2018
Treatments targeting inotropy(Open Access) Maack C, Eschenhagen T, (...), Mebazaa AEuropean Heart Journal2018
German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management(Open Access) Thomas D, Christ T, (...), Voigt NClinical Research in Cardiology2018
Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia(Open Access) Chowdhury A, Aich A, (...), Dudek JCell Reports2018
Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndromePaolacci S, Li Y, (...), Hennekam RCJournal of Medical Genetics2018
Empagliflozin directly improves diastolic function in human heart failure(Open Access) Pabel S, Wagner S, (...), Sossalla SEuropean Journal of Heart Failure2018
Material presented at EAHIL 2018 (Cardiff, UK) in Session CEC 7 (Electronic Laboratory Notebooks)(Open Access) Krause E, Kusch H, Tate DGöttingen Research Online (Data.GRO)2018
ESC Congress 2018 highlights in basic science: a report from the Scientists of Tomorrow(Open Access) Schmidt C, Voigt NCardiovascular Research2018
The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy(Open Access) Ahmad S, Tirilomis P, (...), Sossalla SESC Heart Failure2018
Multiple Localization by Functional Translational ReadthroughBersch K, Lobos Matthei I, Thoms SSub-Cellular Biochemistry2018
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation(Open Access) Danielsen TK, Manotheepan R, (...), Stokke MKPLoS One2018
Ryanodine receptor dysfunction and the resolution revolution: how Nobel Prize-winning techniques transform cardiovascular research(Open Access) Voigt N, Lehnart SECardiovascular Research2018
Titin as a force generating muscle protein under regulatory controlFreundt JK, Linke WAJournal of Applied Physiology2018
The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation(Open Access) Singh S, Lämmle S, (...), Richter FScientific Reports2018
Agonistic and antagonistic roles of fibroblasts and cardiomyocytes on viscoelastic stiffening of engineered human myocardium(Open Access) Schlick SF, Spreckelsen F, (...), Rehfeldt FProgress in Biophysics and Molecular Biology2018
Hallermann-Streiff syndrome: A missing molecular link for a highly recognizable syndromeSchmidt J, Wollnik BAmerican Journal of Medical Genetics Part C-Seminars in Medical Genetics2018
Digital Notebooks - Productivity Tools For Researchers - Event Materials(Open Access) Adams R, Branchett S, (...), Therier JZenodo2018
The Use of Glycosylation Tags as Reporters for Protein Entry into the Endoplasmic Reticulum in Yeast and Mammalian Cells.Buentzel J, Thoms SMethods in Molecular Biology2017
P1334 - The relevant role of SR Ca leak in the development of heart failure(Open Access) Mohamed BA, Kattner L, (...), Toischer KEuropean Journal of Heart Failure2017
P41 - Studying beta-adrenergic signalling in a patient-specific induced pluripotent stem cell model for Takotsubo syndrome(Open Access) Hübscher D, Borchert T, (...), Streckfuß-Bömeke KEuropean Journal of Heart Failure2017
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling(Open Access) Abilez OJ, Tzatzalos E, (...), Wu JCStem Cells2017
Dietary spermidine for lowering high blood pressure(Open Access) Eisenberg T, Abdellatif M, (...), Madeo FAutophagy2017
Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D(Open Access) Gröschel C, Hübscher D, (...), Dressel RFrontiers in Immunology2017
Titin Gene and Protein Functions in Passive and Active MuscleLinke WAAnnual Review of Physiology2017
Collaboration of Heat Shock Protein 70 and Stress-induced NKG2D Ligands in the Activation of NK Cells against TumorsDressel RCurrent Immunology Reviews2017
The contractile adaption to preload depends on the amount of afterload(Open Access) Schotola H, Sossalla ST, (...), Toischer KESC Heart Failure2017
Translating Myocardial Remuscularization.(Open Access) Zimmermann WHCirculation research2017
Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy.(Open Access) Hofhuis J, Bersch K, (...), Thoms SJournal of cell science2017
Defined Engineered Human Myocardium with Advanced Maturation for Applications in Heart Failure Modelling and Repair.(Open Access) Tiburcy M, Hudson JE, (...), Zimmermann WHCirculation2017
Remuscularization of the failing heart.(Open Access) Zimmermann WHJournal of Physiology-London2017
A protocol for registration and correction of multicolour STED superresolution images.(Open Access) Hebisch E, Wagner E, Westphal V, Sieber JJ, Lehnart SEJournal of microscopy2017
Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity.Neef S, Heijman J, (...), El-Armouche ANaunyn-Schmiedebergs Archives of Pharmacology2017
Vortices Termination in the Cardiac MuscleKrinsky VI, Biktashev VN, Otani NF, Luther SNonlinear Systems and Complexity; Advances in Dynamics, Patterns, Cognition2017
Mechanisms of vortices termination in the cardiac muscle.(Open Access) Hornung D, Biktashev VN, (...), Luther SRoyal Society Open Science2017
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure.(Open Access) Schmidt C, Wiedmann F, (...), Thomas DProgress in biophysics and molecular biology2017
Modelling far field pacing for terminating spiral waves pinned to ischaemic heterogeneities in cardiac tissue.(Open Access) Boccia E, Luther S, Parlitz UPhilosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences2017
Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure.(Open Access) Dewenter M, Neef S, (...), El-Armouche ACirculation-Heart Failure2017
PDE2 at the crossway between cAMP and cGMP signalling in the heart.Weber S, Zeller M, Guan K, Wunder F, Wagner M, El-Armouche ACellular Signalling2017
Engineered Heart RepairFujita B, Zimmermann WHClinical Pharmacology and Therapeutics2017
Myocardial Tissue Engineering for Regenerative Applications.(Open Access) Fujita B, Zimmermann WHCurrent Cardiology Reports2017
Generation of a KLF15 homozygous knockout human embryonic stem cell line using paired CRISPR/Cas9n, and human cardiomyocytes derivation(Open Access) Noack C, Haupt LP, Zimmermann WH, Streckfuß-Bömeke K, Zelarayán LCStem Cell Research2017
Opinion paper: Data provenance challenges in biomedical research : it - Information TechnologyBaum B, Bauer CR, (...), Sax UIT-Information Technology2017
P4479 - B-catenin/TCF7L2 signaling orchestrates initiation of pathological hypertrophic cardiac remodeling by inducing chromatin modifications(Open Access) Iyer LM, Noack C, (...), Zelarayán LCEuropean Heart Journal2017
P2545 - Inducible paracrine release of IGF-1 improves heart muscle thickness and function(Open Access) Soong PL, Sur S, (...), Zimmermann WHEuropean Heart Journal2017
5044 - Heat shock protein 47 knockout in fibroblasts causes contractile dysfunction in engineered human myocardium(Open Access) Sur S, Noack C, (...), Zimmermann WHEuropean Heart Journal2017
P5841 - PP1 activation as novel antiarrhythmic approach in human heart failure(Open Access) Eiringhaus J, Fischer TH, (...), Sossalla STEuropean Heart Journal2017
Cardiac optogenetics: using light to monitor cardiac physiology.(Open Access) Koopman CD, Zimmermann WH, Knöpfel T, de Boer TPBasic research in cardiology2017
Technical Aspects of Data Provenance in Clinical Trials(Open Access) Parciak M, Bauer CR, Baum B, Kusch H, Sax UGerman Medical Science GMS Publishing House2017
Towards sustainable research data management in advanced light microscopy(Open Access) Henke C, Kusch H, Marzec B, Nussbeck SY, Umbach NGerman Medical Science GMS Publishing House2017
Emergent dynamics of spatio-temporal chaos in a heterogeneous excitable mediumBitthin P, Berg S, Parlitz U, Luther SChaos2017
State-of-the-Art in Tissue-Engineered Heart RepairFujita B, Tiburcy M, Ensminger S, Zimmermann WHCardiac Regeneration2017
Complex restitution behavior and reentry in a cardiac tissue model for neonatal mice.(Open Access) Mayer A, Bittihn P, Luther SPhysiological reports2017
Role of Cardiolipin in Mitochondrial Signaling Pathways.(Open Access) Dudek JFrontiers in cell and developmental biology2017
Electromechanical optical mapping.(Open Access) Christoph J, Schröder-Schetelig J, Luther SProgress in biophysics and molecular biology2017
Functional correction of dystrophin actin binding domain mutations by genome editing.(Open Access) Kyrychenko V, Kyrychenko S, (...), Olson ENJCI Insight2017
Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.(Open Access) Streckfuß-Bömeke K, Tiburcy M, (...), Guan KJournal of Molecular and Cellular Cardiology2017
Cardiomyocyte proliferation prevents failure in pressure overload but not volume overload.(Open Access) Toischer K, Zhu W, (...), Hasenfuß GJournal of Clinical Investigation2017
De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction.(Open Access) Ehmke N, Graul-Neumann L, (...), Kornak UAmerican journal of human genetics2017
Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.(Open Access) Perera RK, Fischer TH, (...), Nikolaev VOScientific reports2017
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.(Open Access) Richter KN, Revelo NH, (...), Rizzoli SOEMBO journal2017
T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure.(Open Access) Gröschel C, Sasse A, (...), Dressel RScientific reports2017
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal developmentGordon CT, Xue S, (...), Reversade BNature Genetics2017
Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes.(Open Access) Hamdani N, Herwig M, Linke WABiophysical Reviews2017
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy.(Open Access) Borchert T, Hübscher D, (...), Streckfuß-Bömeke KJournal of the American College of Cardiology2017
The Tumorigenicity of Multipotent Adult Germline Stem Cells Transplanted into the Heart Is Affected by Natural Killer Cells and by Cyclosporine A Independent of Its Immunosuppressive Effects.(Open Access) Hübscher D, Kaiser D, Elsner L, Monecke S, Dressel R, Guan KFrontiers in immunology2017
Immunological Properties of Murine Parthenogenetic Stem Cell-Derived Cardiomyocytes and Engineered Heart Muscle(Open Access) Didié M, Galla S, Muppala V, Dressel R, Zimmermann WHFrontiers in Immunology2017
Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation Products(Open Access) Johannsen H, Muppala V, (...), Dressel RFrontiers in Immunology2017
Dataset for: Complex restitution behavior and reentry in a cardiac tissue model for neonatal mice(Open Access) Mayer A, Bittihn P, Luther SFigshare2017
Supplementary material from "Mechanisms of vortices termination in the cardiac muscle"(Open Access) Hornung D, Biktashev VN, (...), Luther SFigshare2017
A new defibrillation mechanism: Termination of reentrant waves by propagating action potentials induced by nearby heterogeneities(Open Access) Han S, Otani NF, Krinski V, Luther SComputing in Cardiology Conference (CinC)2016
The functional readthrough extension of malate dehydrogenase reveals a modification of the genetic code(Open Access) Hofhuis J, Schueren F, (...), Thoms SOpen Biology2016
Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice(Open Access) Gogiraju R, Schroeter MR, (...), Schäfer KCardiovascular Research2016
Antiarrhythmic effects of dantrolene in human diseased cardiomyocytesHartmann N, Pabel S, (...), Sossalla SHeart Rhythm2016
Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury–to–chronic kidney disease progressionTampe B, Steinle U, (...), Zeisberg MKidney International2016
Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction(Open Access) Vettel C, Lindner M, (...), El-Armouche ACirculation Research2016
Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by InjuryOtt C, Martens H, (...), Ehrenreich HMolecular Medicine2016
hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities(Open Access) Veerman CC, Mengarelli I, (...), Bezzina CRScientific Reports2016
Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia PreventionChowdhury SK, Liu W, (...), Wang XCirculation2016
Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective methodLiu X, Qi J, Xu X, Zeisberg M, Guan K, Zeisberg EMDifferentiation2016
Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure.(Open Access) Fischer TH, Herting J, (...), Sossalla SEuropace2016
Strip and Dress the Human Heart(Open Access) Zimmermann WHCirculation Research2016
A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1.(Open Access) Kilisch M, Lytovchenko O, Arakel EC, Bertinetti D, Schwappach BJournal of Cell Science2016
Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome.(Open Access) Dudek J, Cheng IF, (...), Rehling PEMBO molecular medicine2016
The molecular and functional identities of atrial cardiomyocytes in health and disease.(Open Access) Brandenburg S, Arakel EC, Schwappach B, Lehnart SEBiochimica et Biophysica Acta-Molecular Cell Research2016
Long-Term Oocyte-Like Cell Development in Cultures Derived from Neonatal Marmoset Monkey Ovary.(Open Access) Fereydouni B, Salinas-Riester G, (...), Behr RStem Cells International2016
The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA.(Open Access) Isernhagen A, Schilling D, (...), Dressel RImmunogenetics2016
Bifurcations, chaos, and sensitivity to parameter variations in the Sato cardiac cell model(Open Access) Ottea S, Berg S, Luther S, Parlitz UCommunications in Nonlinear Science and Numerical Simulation2016
Inhibition of CaMKII Attenuates Progressing Disruption of Ca2+ Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure.Fischer TH, Kleinwächter A, (...), Sossalla SArtificial Organs2016
DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition.(Open Access) Tan X, Xu X, Zeisberg M, Zeisberg EMPLoS One2016
High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation.Tan X, Xu X, Zeisberg EM, Zeisberg MBiochemical and Biophysical Research Communications2016
The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology.Hartmann N, Mason FE, (...), Sossalla SJournal of Molecular and Cellular Cardiology2016
The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine.Mason FE, Sossalla SJournal of Cardiovascular Pharmacology and Therapeutics2016
"Reduced" Coumarin Dyes with an O-Phosphorylated 2,2-Dimethyl-4-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline Fragment: Synthesis, Spectra, and STED Microscopy.Nizamov S, Sednev MV, (...), Hell SWChemistry-A European Journal2016
The transcriptomes of novel marmoset monkey embryonic stem cell lines reflect distinct genomic features.(Open Access) Debowski K, Drummer C, (...), Behr RScientific Reports2016
Isolation and Primary Culture of Adult Mouse Cardiac Fibroblasts(Open Access) Zafeiriou MP, Noack C, Zelarayán LCBio-Protocol2016
Axial tubule junctions control rapid calcium signaling in atria.(Open Access) Brandenburg S, Kohl T, (...), Lehnart SEJournal of Clinical Investigation2016
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles(Open Access) Qin X, Riegler J, (...), Wu JCCirculation-Cardiovascular Imaging2016
Cardioprotection and lifespan extension by the natural polyamine spermidine.Eisenberg T, Abdellatif M, (...), Madeo FNature Medicine2016
Titin-truncating variants affect heart function in disease cohorts and the general population.(Open Access) Schafer S, de Marvao A, (...), Cook SANature Genetics2016
Optogenetic Light Crafting Tools for the Control of Cardiac Arrhythmias.Richter C, Christoph J, Lehnart SE, Luther SMethods in Molecular Biology2016
Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release.(Open Access) Manotheepan R, Danielsen TK, (...), Stokke MKCardiovascular Research2016
Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET.(Open Access) Sprenger JU, Bork NI, Herting J, Fischer TH, Nikolaev VOPLoS One2016
Spontaneous Termination of Reentrant Activity under Myocardial Acute Ischemia: Role of Cellular Conductivity and its Relation to Ischemic Heterogeneities(Open Access) Boccia E, Parlitz U, Luther SCommunications in Nonlinear Science and Numerical Simulation2016
Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks.(Open Access) Isernhagen A, Malzahn D, Bickeböller H, Dressel RFrontiers in Immunology2016
Scanning and resetting the phase of a pinned spiral wave using periodic far field pulses(Open Access) Shajahan TK, Berg S, Luther S, Krinski V, Bittihn PNew Journal of Physics2016
Erratum to: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury(Open Access) Ott C, Martens H, (...), Ehrenreich HMolecular Medicine2016
Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo.(Open Access) Rivera-Monroy J, Musiol L, (...), Vilardi FScientific reports2016
Generation of human induced pluripotent stem cells using non-synthetic mRNA.(Open Access) Rohani L, Fabian C, (...), Stolzing AStem cell research2016
Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice.(Open Access) Gogiraju R, Xu X, (...), Schäfer KJournal of the American Heart Association2015
Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy.(Open Access) Perera RK, Sprenger JU, (...), Nikolaev VOCirculation research2015
Entropy Rate Maps of Complex Excitable Dynamics in Cardiac Monolayers(Open Access) Schlemmer A, Berg S., Shajahan TK, Luther S, Parlitz UEntropy2015
Sensing Cardiac Electrical Activity With a Cardiac Myocyte Targeted Optogenetic Voltage Indicator.(Open Access) Chang Liao ML, de Boer T, (...), Zimmermann WHCirculation research2015
Basin structure of optimization based state and parameter estimationSchumann-Bischoff J, Parlitz U, (...), Luther SChaos2015
Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation.Godier-Furnémont AF, Tiburcy M, (...), Zimmermann WHBiomaterials2015
I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model(Open Access) Friedrich FW, Sotoud H, (...), El-Armouche AIJC Heart & Vasculature2015
Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2.(Open Access) Zaglia T, Pianca N, (...), Mongillo MProceedings of the National Academy of Sciences of the United States of America2015
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.(Open Access) Hinson JT, Chopra A, (...), Seidman CEScience2015
Metadata capture in an electronic notebook: How to make it as simple as possible?(Open Access) Menzel J, Weil P, Nussbeck SYGMS Medizinische Informatik, Biometrie und Epidemiologie2015
Mechanical stimulation in the engineering of heart muscle.Liaw NY, Zimmermann WHAdvanced Drug Delivery Reviews2015
Human Engineered Heart Muscles Engraft and Survive Long-Term in a Rodent Myocardial Infarction Model.(Open Access) Riegler J, Tiburcy M, (...), Wu JCCirculation research2015
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.Sharma P, Abbasi C, (...), Gramolini AONature Communications2015
Stabilization of three-dimensional scroll waves and suppression of spatiotemporal chaos by heterogeneitiesSpreckelsen F, Hornung D, Steinbock O, Parlitz U, Luther SPhysical Review E2015
Tracking of Inhaled Near-Infrared Fluorescent Nanoparticles in Lungs of SKH-1 Mice with Allergic Airway Inflammation.Markus MA, Napp J, (...), Alves FACS nano2015
On the Adjacency Matrix of RyR2 Cluster Structures.(Open Access) Walker MA, Kohl T, Lehnart SE, Greenstein JL, Lederer WJ, Winslow RLPLoS computational biology2015
Molecular and structural transition mechanisms in long-term volume overload.(Open Access) Mohamed BA, Schnelle M, (...), Toischer KEuropean journal of heart failure2015
In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease.(Open Access) Sprenger JU, Perera RK, (...), Nikolaev VONature Communications2015
Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII.(Open Access) Fischer TH, Herting J, (...), Sossalla SCardiovascular Research2015
Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.(Open Access) Meijer van Putten RM, Mengarelli I, (...), Wilders RFrontiers in physiology2015
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.(Open Access) Kruse V, Hamann C, (...), Dressel RPLoS One2015
Ca(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKII.(Open Access) Johnston AS, Lehnart SE, Burgoyne JRFrontiers in Pharmacology2015
Intensity matters: Ryanodine receptor regulation during exercise.(Open Access) Kohl T, Weninger G, Zalk R, Eaton P, Lehnart SEProceedings of the National Academy of Sciences of the United States of America2015
Association of circulating angiogenesis inhibitors and asymmetric dimethyl arginine with coronary plaque burden.(Open Access) Charytan DM, Cinelli A, Zeisberg EMFibrogenesis & tissue repair2015
Association of activated vitamin D use with myocardial fibrosis and capillary supply: results of an autopsy study.(Open Access) Charytan DM, Padera RF, Helfand AM, Zeisberg EMRenal Failure2015
Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition.(Open Access) Xu X, Friehs I, (...), Zeisberg EMCirculation research2015
Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis.(Open Access) Xu X, Tan X, (...), Zeisberg EMCardiovascular Research2015
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease.(Open Access) Hartmann S, Ridley AJ, Lutz SFrontiers in Pharmacology2015
p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts.Ongherth A, Pasch S, (...), Lutz SJournal of Molecular and Cellular Cardiology2015
RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes.(Open Access) Jatho A, Hartmann S, (...), Lutz SPLoS One2015
Crosstalk of cardiomyocytes and fibroblasts in co-cultures.(Open Access) Rother J, Richter C, (...), Tarantola MOpen Biology2015
Changes of sleep-stage transitions due to ageing and sleep disorder.(Open Access) Schlemmer A, Parlitz U, Luther S, Wessel N, Penzel TPhilosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences2015
Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach.(Open Access) Debowski K, Warthemann R, (...), Behr RPLoS One2015
The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation.(Open Access) Isernhagen A, Malzahn D, (...), Dressel REMBO molecular medicine2015
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.(Open Access) Montes-Cobos E, Li X, (...), Reichardt HMPLoS One2015
Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting.(Open Access) Xu X, Smorag L, (...), Pantakani DVNature Communications2015
Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies.(Open Access) Pacheu-Grau D, Bareth B, (...), Deckers MCell metabolism2015
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane.(Open Access) Pfaff J, Monroy JR, (...), Kehlenbach RHJournal of cell science2015
Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C.(Open Access) Amanzada A, Reinhardt L, Fey D, Zeisberg EM, Mihm SPLoS One2015
Datenorganisation eines klinischen Sonderforschungsbereiches in einer integrierten, langfristig verfügbaren Forschungsdatenplattform(Open Access) Kusch H, Schmitt O, Marzec B, Nussbeck SY,German Medical Science GMS Publishing House2015
Quantifying spatiotemporal complexity of cardiac dynamics using ordinal patternsSchlemmer A, Berg S, Shajahan TK, Luther S, Parlitz U,2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)2015
S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding(Open Access) Alegre-Cebollada J, Kosuri P, (...), Cell2014
Ins Herz des sekretorischen Pfades: Stress mobilisiert Ionenkanäle(Open Access) Arakel EC, Schwappach B,BIOspektrum2014
Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes(Open Access) Arakel EC, Brandenburg S, (...), Journal of Cell Science2014
Emerging importance of oxidative stress in regulating striated muscle elasticity(Open Access) Beckendorf L, Linke WA,Journal of Muscle Research and Cell Motility2014
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthaseBelge C, Hammond J, (...), Circulation2014
Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease(Open Access) Charytan DM, Padera R, (...), International Journal of Cardiology2014
Aim24 stabilizes respiratory chain supercomplexes and is required for efficient respiration(Open Access) Deckers M, Balleininger M, (...), FEBS letters2014
The Janus face of BNP therapy in chronic heart failure: beneficial effects unmasked by β blockers?Dewenter M, Vettel V, El-Armouche A,Heart2014
Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa(Open Access) Dybkova N, Wagner S, (...), Cardiovascular Research2014
Ca(2+) /calmodulin-dependent protein kinase II equally induces sarcoplasmic reticulum Ca(2+) leak in human ischaemic and dilated cardiomyopathyFischer TH, Eiringhaus J, (...), European Journal of Heart Failure2014
Herzinsuffizienz: "From Bench to Bedside" - Neues im Bereich der IonenhomöostaseFörster A, Maier LS,Journal für Kardiologie2014
Transgenic Mice for Real-Time Visualization of cGMP in Intact Adult CardiomyocytesGötz KR, Sprenger JU, (...), Circulation Research2014
Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathologyKöhler AC, Sag CM, Maier LSJournal of Molecular and Cellular Cardiology2014
Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins(Open Access) Kötter S, Unger A, (...), Journal of Cell Biology2014
Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial HypertrophyKreusser MM, Lehmann LH, (...), Circulation2014
Gigantic business: titin properties and function through thick and thinLinke WA, Hamdani NCirculation Research2014
Experimental antiarrhythmic targets: CaMKII inhibition - ready for clinical evaluation?Maier LS,Current Medicinal Chemistry2014
CaMKII regulation of cardiac K channels(Open Access) Mustroph J, Maier LS, Wagner S,Frontiers in Pharmacology2014
Paradoxical Effects on Force Generation after Efficient β1-Adrenoceptor Knockdown in Reconstituted Heart TissueNeuber C, Müller OJ, (...), El-Armouche AJournal of Pharmacology and Experimental Therapeutics2014
The laboratory notebook in the 21st century(Open Access) Nussbeck SY, Weil P, (...), EMBO reports2014
Detecting synchronization and interrelations in multivariate time seriesParlitz U, Luther S,2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)2014
Local observability of state variables and parameters in nonlinear modeling quantified by delay reconstructionParlitz U, Schumann-Bischoff J, Luther SChaos2014
Quantifying uncertainty in state and parameter estimationParlitz U, Schumann-Bischoff J, Luther S,Physical Review E2014
Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent mannerSag CM, Mallwitz A, (...), Journal of Molecular and Cellular Cardiology2014
Evaluation of machine learning methods for the long-term prediction of cardiac diseasesSchlemmer A, Zwirnmann H, Zabel M, Parlitz U, Luther S,2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)2014
Eliminating pinned spiral waves in cardiac monolayer by far field pacingShajahan TK, Krinski VI, Knyazeva S, Luther S,2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)2014
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytesSlimane ZH, Bedioune I, (...), Cardiovascular Research2014
Effects of ranolazine on torsades de pointes tachycardias in a healthy isolated rabbit heart model(Open Access) Sossalla S, Wallisch N, (...), Cardiovascular Therapeutics2014
Induction of Tet3-dependent epigenetic remodeling by low-dose Hydralazine attenuates progression of chronic kidney disease(Open Access) Tampe B, Tampe D, (...), EBioMedicine2014
Collagen-Based Engineered Heart MuscleTiburcy M, Meyer T, Soong PL, Zimmermann WH,Methods in molecular biology2014
Modeling myocardial growth and hypertrophy in engineered heart muscleTiburcy M, Zimmermann WH,Trends in Cardiovascular Medicine2014
Dopamine and Lipophilic Derivates Protect Cardiomyocytes against Cold Preservation InjuryVettel C, Hottenrott MC, (...), Journal of Pharmacology and Experimental Therapeutics2014
PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathwaysVettel C, Lämmle S, (...), American Journal of Physiology-Heart and Circulatory Physiology2014
Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function(Open Access) Voelkel T, Andresen C, (...), Biochimica et Biophysica Acta-Molecular Cell Research2014
Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles(Open Access) Wagner E, Brandenburg S, Kohl T, Lehnart SE,Journal of Visualized Experiments2014
NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKIIWagner S, Dantz C, (...), Journal of Molecular and Cellular Cardiology2014
Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177(Open Access) Walther S, Pluteanu F, (...), American Journal of Physiology-Heart and Circulatory Physiology2014
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signalingWright PT, Nikolaev VO, (...), Journal of Molecular and Cellular Cardiology2014
Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarctionZafiriou MP, Noack C, (...), Zelarayán LCStem Cells2014
Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure(Open Access) Zeisberg M, Tampe B, (...), American Journal of Pathology2014
Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis.(Open Access) Tampe B, Tampe D, (...), Zeisberg MJournal of the American Society of Nephrology2014
Lights on for HIF-1α: genetically enhanced mouse cardiomyocytes for heart tissue imaging.(Open Access) Hesse AR, Levent E, Zieseniss A, Tiburcy M, Zimmermann WH, Katschinski DMCellular Physiology and Biochemistry2014
miR-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction.(Open Access) Izarra A, Moscoso I, (...), Bernad AStem Cell Reports2014
Minimierung des Dokumentationsaufwandes für die medizinische Grundlagenforschung mithilfe eines elektronischen Laborbuches: Aufgezeigt am Beispiel eines Western Blot Metadatenschemata(Open Access) Menzel J, Weil, P, Nussbeck SY,German Medical Science GMS Publishing House2014
Anbindung eines elektronischen Laborbuchs an eine vorhandene Langzeitarchivierungsinfrastruktur(Open Access) Marzec B, Weil P, Nussbeck SY,German Medical Science GMS Publishing House2014
Integrierte Portalumgebung und verteilte Echtzeitsuche für medizinische Langzeitarchivierung(Open Access) Schmitt O, Weil P, Wieder P, Nussbeck SY,German Medical Science GMS Publishing House2014
Cardiac Progenitor Cells and their Therapeutic Application for Cardiac Repair(Open Access) Cyganek L, Chen S, Borchert T, Guan K,Journal of Clinical & Experimental Cardiology2013
Parthenogenetic stem cells for tissue-engineered heart repair(Open Access) Didie M, Christalla P, (...), Journal of Clinical Investigation2013
Preservation of left ventricular function and morphology in volume-loaded versus volume-unloaded heterotopic heart transplantsDidie M, Biermann D, (...), American Journal of Physiology-Heart and Circulatory Physiology2013
Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome(Open Access) Dudek J, Cheng IF, (...), Stem Cell Research2013
Ca2+/calmodulin-dependent protein kinase II and protein kinase A differentially regulate sarcoplasmic reticulum Ca2+ leak in human cardiac pathologyFischer TH, Herting J, (...), Circulation2013
The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies?(Open Access) Fischer TH, Neef S, Maier LS,Journal of Molecular and Cellular Cardiology2013
The ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisis(Open Access) Fischer TH, Maier LS, Sossalla S,Heart Failure Reviews2013
Advances and techniques to measure cGMP in intact cardiomyocytesGötz KR, Nikolaev VO,Methods in Molecular Biology2013
Archivierung von Genomdaten(Open Access) Grütz R, Mathieu N, Löhnhardt B, Weil P, Krawczak M,Medizinische Genetik2013
Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction(Open Access) Hamdani N, Bishu KG, von Frieling-Salewsky M, Redfield MM, Linke WA,Cardiovascular Research2013
Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylationHamdani N, Krysiak J, (...), Circulation Research2013
Special issue "Novel perspectives on heart failure"(Open Access) Hasenfuß G, Heusch GBasic Research in Cardiology2013
Function and regulation of serine/threonine phosphatases in the healthy and diseased heartHeijman J, Dewenter M, El-Armouche A, Dobrev D,Journal of Molecular and Cellular Cardiology2013
Imaging T-tubules: dynamic membrane structures for deep functions(Open Access) Kohl T, Lehnart SE,Cardiovascular Research2013
Superresolution microscopy in heart - cardiac nanoscopy(Open Access) Kohl T, Westphal V, Hell SW, Lehnart SEJournal of Molecular and Cellular Cardiology2013
Understanding the physiology of heart failure through cellular and in vivo models-towards targeting of complex mechanisms(Open Access) Lehnart SE,Experimental Physiology2013
RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study(Open Access) Maier LS, Layug B, (...), JACC-Heart failure2013
The late Na current as a therapeutic target: where are we?Maier LS, Sossalla S,Journal of Molecular and Cellular Cardiology2013
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytesMehel H, Emons J, (...), Journal of the American College of Cardiology2013
Requirement analysis for an electronic laboratory notebook for sustainable data management in biomedical researchMenzel J, Weil P, (...), Studies in Health Technology and Informatics2013
Novel aspects of excitation-contraction coupling in heart failureNeef S, Maier LS,Basic Research in Cardiology2013
While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO miceNeef S, Sag CM, (...), Journal of Molecular and Cellular Cardiology2013
Compartmentation of cAMP signalling in cardiomyocytes in health and diseasePerera RK, Nikolaev VO,Acta Physiologica2013
Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation(Open Access) Purohit A, Rokita AG, (...), Circulation2013
The four and a half LIM-domain 2 controls early cardiac cell commitment and expansion via regulating β-catenin-dependent transcription(Open Access) Renger A, Zafiriou MP, (...), Stem Cells2013
Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII(Open Access) Sag CM, Wolff HA, (...), Basic Research in Cardiology2013
Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytesSag CM, Wagner S, Maier LS,Free Radical Biology and Medicine2013
Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading(Open Access) Schwoerer AP, Neef S, (...), Pflugers Archiv-European Journal of Physiology2013
Ranolazine maintained sinus rhythm in a patient with refractory symptomatic atrial fibrillation(Open Access) Sossalla S, Sohns C, (...), Cardiovascular Therapeutics2013
Development of a colorimetric and a fluorescence phosphatase-inhibitor assay suitable for drug discovery approachesSotoud H, Gribbon P, (...), Journal of Biomolecular Screening2013
Biophysical Techniques for Detection of cAMP and cGMP in Living Cells(Open Access) Sprenger JU, Nikolaev VO,International Journal of Molecular Sciences2013
Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts(Open Access) Streckfuß-Bömeke K, Wolf F, (...), European Heart Journal2013
Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart diseaseToischer K, Hartmann N, (...), Journal of Molecular and Cellular Cardiology2013
Redox regulation of sodium and calcium handlingWagner S, Rokita AG, Anderson ME, Maier LS,Antioxidants & Redox Signaling2013
Small conductance Ca-activated K channel: Small but powerful proarrhythmogenic?Wagner S, Maier LS,Heart Rhythm2013
Patching the Heart Cardiac Repair From Within and OutsideYe L, Zimmermann WH, Garry DJ, Zhang J,Circulation Research2013
The role of promoter hypermethylation in fibroblast activation and fibrogenesis(Open Access) Zeisberg EM, Zeisberg M,Journal of Pathology2013
Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair(Open Access) Zimmermann WH,Stem Cell Research & Therapy2013
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII.(Open Access) Luo M, Guan X, (...), Anderson MEJournal of Clinical Investigation2013
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.(Open Access) Abonnenc M, Nabeebaccus AA, (...), Mayr MCirculation research2013
Nonlinear system identification employing automatic differentiationSchumann-Bischoff J, Luther S, Parlitz UCommunications in Nonlinear Science and Numerical Simulation2013
Vorbereitungsprozess für die elektronische Dokumentation und Nachnutzbarkeit von FD in ELN(Open Access) Marzec B, Weil P, Nussbeck SY,German Medical Science GMS Publishing House2013
New Treatment Options for Late Na Current, Arrhythmias, and Diastolic Dysfunction(Open Access) Maier LS,Current Heart Failure Reports2012
Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction(Open Access) Wagner E, Lauterbach MA, (...), Circulation Research2012